<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">aids</journal-id><journal-title-group><journal-title xml:lang="ru">ВИЧ-инфекция и иммуносупрессии</journal-title><trans-title-group xml:lang="en"><trans-title>HIV Infection and Immunosuppressive Disorders</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2077-9828</issn><publisher><publisher-name>Baltic Medical Education Center</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22328/2077-9828-2023-15-2-59-68</article-id><article-id custom-type="elpub" pub-id-type="custom">aids-810</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL STUDIES</subject></subj-group></article-categories><title-group><article-title>Приверженность лечению у молодых людей с перинатальной ВИЧ-инфекцией в первые годы после перехода из педиатрической во взрослую медицинскую службу</article-title><trans-title-group xml:lang="en"><trans-title>Adherence to treatment in young people with perinatal HIV infection in the first years after transition from pediatric to the adult medical service</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6962-3914</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сафонова</surname><given-names>П. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Safonova</surname><given-names>P. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сафонова Полина Владимировна — кандидат психологических наук, медицинский психолог отдела медицинской и социальной психологии</p><p>190103, Санкт-Петербург, наб. Обводного канала, д. 179</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><email xlink:type="simple">polinasafonova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1866-0926</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кольцова</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Koltsova</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кольцова Ольга Владимировна — кандидат психологических наук, доцент кафедры клинической психологии</p><p>199178, Санкт-Петербург, 12-я линия В.О., д. 13, лит. А</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><email xlink:type="simple">ovkoltsova@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Центр по профилактике и борьбе со СПИД и инфекционными заболеваниями</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St. Petersburg Center for Control of AIDS and Infectious Diseases</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Санкт-Петербургский государственный институт психологии и социальной работы</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St. Petersburg State Institute of Psychology and Social Work</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>21</day><month>07</month><year>2023</year></pub-date><volume>15</volume><issue>2</issue><fpage>59</fpage><lpage>68</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сафонова П.В., Кольцова О.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Сафонова П.В., Кольцова О.В.</copyright-holder><copyright-holder xml:lang="en">Safonova P.V., Koltsova O.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://hiv.bmoc-spb.ru/jour/article/view/810">https://hiv.bmoc-spb.ru/jour/article/view/810</self-uri><abstract><sec><title>Цель</title><p>Цель. Оценить приверженность АРТ и непрерывность лечения у молодых людей, живущих с ВИЧ с рождения или детства, в первые годы после перехода из детской во взрослую службу Центра СПИД, а также проанализировать факторы, связанные с нарушением приверженности лечению после перехода во взрослое отделение.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. В нашем исследовании получены с помощью аудита медицинских карт и проанализированы случаи 86 молодых людей, живущих с ВИЧ с рождения или детства, среди которых 53,5% девушки и 64,0% проживали дома на момент своего 18-летия, и которые более одного года назад переведены из детской во взрослую службу Центра СПИД.</p><p>Результаты и их обсуждение. Большинство (92%) молодых людей, живущих с ВИЧ с рождения или детства, удержались в системе медицинской помощи в первый год после перехода, но лишь 53–62% высоко привержены лечению и наблюдению по поводу ВИЧ-инфекции в первые нескольких лет после перехода. Случаи неприверженности лечению в период детско-подросткового возраста, «более сложная» схема АРТ и отсутствие социальной поддержки взрослого на момент совершеннолетия повышают вероятность нарушения приверженности лечению в первый год после перехода во взрослую службу, а сочетание этих факторов имеет негативные последствия для приверженности и непрерывности лечения в течение более длительного периода времени.</p></sec><sec><title>Заключение</title><p>Заключение. Успешный переход из педиатрической во взрослую службу для пациентов, живущих с ВИЧ с рождения или детства, требует особого дополнительного внимания медицинской системы, способствует сохранению индивидуального здоровья каждого пациента, ставит своей целью остановить ВИЧ во втором поколении.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Objective</title><p>Objective. To assess ART adherence and treatment continuity in young adults living with HIV since birth or childhood in the first years after transition from paediatric to adult service of the AIDS Center, as well as to analyse factors associated with treatment adherence interruption after transition to adult care.</p></sec><sec><title>Materials and methods</title><p>Materials and methods. In our study, 86 cases of young people living with HIV since birth or childhood were obtained by chart audit and analyzed, among whom 53.5% were girls and 64.0% lived at home at the time of their 18th birthday, who have been transferred from paediatric to adult care of the AIDS Center for more than one year.</p></sec><sec><title>Results and discussion</title><p>Results and discussion. The majority (92%) of young adults living with HIV since birth or childhood retained in the health care system in the first year after the transition, but only 53–62% were highly adherent to treatment and monitoring for HIV infection in the first years after the transition. Episodes of non-adherence to treatment during childhood and adolescence, «more complex» ART scheme and the lack of adult’s social support at the time of 18th birthday increase the likelihood of interruption in treatment adherence in the first year after transition to adult care, while the combination of these factors has negative consequences for adherence and continuity of treatment for a longer period of time.</p></sec><sec><title>Conclusion</title><p>Conclusion. Successful transition from paediatric to adult care for patients living with HIV since birth or childhood requires special additional attention of the health care system, contributes to the health protection of each patient, aims to stop HIV in the second generation.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>молодые люди</kwd><kwd>живущие с ВИЧ с рождения или детства (МЛЖВ)</kwd><kwd>приверженность лечению</kwd><kwd>социальная поддержка</kwd><kwd>переход из педиатрической службы во взрослую сеть</kwd></kwd-group><kwd-group xml:lang="en"><kwd>young people living with HIV since birth or childhood (YPLHIV)</kwd><kwd>adherence to treatment</kwd><kwd>social support</kwd><kwd>transition from pediatric to adult service</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Акулова М.В. Методы оценки, контроля и повышения приверженности антиретровирусной терапии: методическое пособие для медицинских специалистов по вопросам приверженности пациентов с ВИЧ-инфекцией АРВ-терапии. Фонд МСП, 2016. 72 с.</mixed-citation><mixed-citation xml:lang="en">Akulova M.V. Methods of adherences creening, control, andenhancement. Guideline for medicals pecialistson ART adherence in patients with HIV-infection. MSP Foundation, 2016. 72 p. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Афонина Л.Ю., Воронин Е.Е., Городнова М.Ю. и др. Медикаментозная приверженность у подростков с ВИЧ-инфекцией (факторы, барьеры, методы оценки и повышения): методические рекомендации. СПб., 2021. 44 с.</mixed-citation><mixed-citation xml:lang="en">Afonina L.Yu., Voronin E.E., Gorodnova M.Yu. et al. Medication adheren ceinadoles cents with HIV-infection (factors, barriers, assess ment and enhancement methods). Guidelines. St. Petersburg, 2021. 44 p. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Casale M., Carlqvist A., Cluver L. Recent Interventions to Improve Retention in HIV Care and Adherence to Antiretroviral Treatment Among Adolescents and Youth: A Systematic Review // AIDS Patient Care STDS. 2019. Jun 1; Vol. 33, No. 6. Р. 237–252. Published online 2019 Jun 3. doi: 10.1089/apc.2018.0320.</mixed-citation><mixed-citation xml:lang="en">Casale M., Carlqvist A., Cluver L. Recent Interventions to Improve Retention in HIV Care and Adherence to Antiretroviral Treatment Among Adolescents and Youth: A Systematic Review // AIDS Patient Care STDS. 2019. Jun 1; Vol. 33, No. 6. Р. 237–252. Published online 2019 Jun 3. doi: 10.1089/apc.2018.0320.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Foster C. CHIVA Guidance on Transition for adolescents living with HIV. Updated: August 2021. Next review date: August 2023. 19 p. [URL: https://www.chiva.org.uk/files/6916/3541/0779/CHIVA_Transition_Guidelines_2021.pdf ]</mixed-citation><mixed-citation xml:lang="en">Foster C. CHIVA Guidance on Transition for adolescents living with HIV. Updated: August 2021. Next review date: August 2023. 19 p. [URL: https://www.chiva.org.uk/files/6916/3541/0779/CHIVA_Transition_Guidelines_2021.pdf ]</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Koenig L.J., Nesheim S., Abramowitz S. Adolescents with perinatally acquired HIV: emerging behavioral and health needs for long-term survivors // Curr. Opin. Obstet Gynecol. 2011; Oct; Vol. 23, No. 5. Р. 321–327. doi: 10.1097/GCO.0b013e32834a581b.</mixed-citation><mixed-citation xml:lang="en">Koenig L.J., Nesheim S., Abramowitz S. Adolescents with perinatally acquired HIV: emerging behavioral and health needs for long-term survivors // Curr. Opin. Obstet Gynecol. 2011; Oct; Vol. 23, No. 5. Р. 321–327. doi: 10.1097/GCO.0b013e32834a581b.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Леонтьев Д.А., Александрова Л.А., Лебедева А.А. Развитие личности и психологическая поддержка учащихся с ОВЗ в условиях инклюзивного профессионального образования. М.: Смысл, 2017. 79 с.</mixed-citation><mixed-citation xml:lang="en">Leontiev D.A., Alexandrova L.A., Lebedeva A.A. Personality development and psychological support of students with health limitations in inclusive professional education. Moscow: publishing house Smysl, 2017. 79 p. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Сафонова П.В., Кольцова О.В. Психосексуальные потребности и сексуальное поведение подростков, живущих с ВИЧ с детства // ВИЧ-инфекция и иммуносупрессии. 2021. Т. 13, № 2. С. 108–115. https://doi.org/10.22328/2077-9828-2021-13-2-108-115.</mixed-citation><mixed-citation xml:lang="en">Safonova P.V., Koltsova O.V. Рsychosexual needs and sexual behavior of adolescents living with HIV since infancy. HIV Infection and Immunosuppressive Disorders, 2021, Vol. 13, No. 2, рр. 108–115 (In Russ.). https://doi.org/10.22328/2077-9828-2021-13-2-108-115.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Biersteker S. Outcomes of Transition to Adult HV Care in Perinatally HIV-infected Young Adults. 2016. FIU Electronic Theses and Dissertations. 3041. https://digitalcommons.fiu.edu/etd/3041.</mixed-citation><mixed-citation xml:lang="en">Biersteker S. Outcomes of Transition to Adult HV Care in Perinatally HIV-infected Young Adults. 2016. FIU Electronic Theses and Dissertations. 3041. https://digitalcommons.fiu.edu/etd/3041.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Ryscavage P., Macharia T., Patel D. et al. Linkage to and retention in care following healthcare transition from pediatric to adult HIV care // AIDS Care. 2016. Vol. 28, No. 5. Р. 561–565. doi: 10.1080/09540121.2015.1131967.</mixed-citation><mixed-citation xml:lang="en">Ryscavage P., Macharia T., Patel D. et al. Linkage to and retention in care following healthcare transition from pediatric to adult HIV care // AIDS Care. 2016. Vol. 28, No. 5. Р. 561–565. doi: 10.1080/09540121.2015.1131967.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Philbin M.M., Tanner A.E., Ma A. et al. Adolescent and Adult HIV Providers’ Definitions of HIV-Infected Youths’ Successful Transition to Adult Care in the United States // IDS Patient Care STDS. 2017. Oct; Vol. 31, Nо. 10. Р. 421–427. doi: 10.1089/apc.2017.0131.</mixed-citation><mixed-citation xml:lang="en">Philbin M.M., Tanner A.E., Ma A. et al. Adolescent and Adult HIV Providers’ Definitions of HIV-Infected Youths’ Successful Transition to Adult Care in the United States // IDS Patient Care STDS. 2017. Oct; Vol. 31, Nо. 10. Р. 421–427. doi: 10.1089/apc.2017.0131.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Hussen S.A., Chakraborty R., Knezevic A. et al. Transitioning young adults from paediatric to adult care and the HIV care continuum in Atlanta, Georgia, USA: a retrospective cohort study // J. Int. AIDS Soc. 2017. Sep 1. Vol. 20, Nо. 1. Р. 21848. doi: 10.7448/IAS.20.1.21848.</mixed-citation><mixed-citation xml:lang="en">Hussen S.A., Chakraborty R., Knezevic A. et al. Transitioning young adults from paediatric to adult care and the HIV care continuum in Atlanta, Georgia, USA: a retrospective cohort study // J. Int. AIDS Soc. 2017. Sep 1. Vol. 20, Nо. 1. Р. 21848. doi: 10.7448/IAS.20.1.21848.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Воропаева Е.К., Самарина А.В., Ястребова Е.Б. и др. Сложности при переводе ВИЧ-инфицированных подростков во взрослую сеть наблюдения // Актуальные вопросы ВИЧ-инфекции. Материалы Международной научно-практической конференции. 2016. С. 237–238.</mixed-citation><mixed-citation xml:lang="en">Voropaeva E.K., Samarina A.V., Yastrebova E.B. et al. Difficulties by transitioning HIV-infected adoles cents to adultcare. Curren tissues of HIV-infection. Materials of international research and practical conference. 2016, pp. 237–238 (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Shulman R., Shah B.R., Fu L. et al. Diabetes transition care and adverse events: a population-based cohort study in Ontario, Canada // Diabet. Med. 2018 Nov. Vol. 35, Nо. 11. Р. 1515–1522.</mixed-citation><mixed-citation xml:lang="en">Shulman R., Shah B.R., Fu L. et al. Diabetes transition care and adverse events: a population-based cohort study in Ontario, Canada // Diabet. Med. 2018 Nov. Vol. 35, Nо. 11. Р. 1515–1522.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Подростки, живущие с ВИЧ: развитие и усиление услуг по уходу и поддержке. Детский фонд Организации Объединенных Наций (ЮНИСЕФ). 2017. 174 с. https://ecom.ngo/wp-content/uploads/2018/01/Teens-with-HIV-UNICEF-2017.pdf URL: https://www.unicef.org/eca/media/1011/file.</mixed-citation><mixed-citation xml:lang="en">Adolescents living with HIV: Developing and strengthening support services. UNICEF. 2016. 148 p. (In Russ.). URL: https://www.unicef.org/eca/media/1011/file.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Tepper V., Zaner S., Ryscavage P. HIV healthcare transition outcomes among youth in North America and Europe: a review // J. Int. AIDS Soc. 2017. Vol. 20, Suppl. 3. Р. 21490. doi: 10.7448/IAS.20.4.21490.</mixed-citation><mixed-citation xml:lang="en">Tepper V., Zaner S., Ryscavage P. HIV healthcare transition outcomes among youth in North America and Europe: a review // J. Int. AIDS Soc. 2017. Vol. 20, Suppl. 3. Р. 21490. doi: 10.7448/IAS.20.4.21490.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Lam P.K., Fidler S., Foster C. A review of transition experiences in perinatally and behaviourally acquired HIV-1 infection; same, same but different? // J. Int. AIDS Soc. 2017. May 16, Vol. 20, Suppl. 3. Р. 21506. doi: 10.7448/IAS.20.4.21506.</mixed-citation><mixed-citation xml:lang="en">Lam P.K., Fidler S., Foster C. A review of transition experiences in perinatally and behaviourally acquired HIV-1 infection; same, same but different? // J. Int. AIDS Soc. 2017. May 16, Vol. 20, Suppl. 3. Р. 21506. doi: 10.7448/IAS.20.4.21506.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Drageset J. Health Promotion in Health Care // Vital Theories and Research. First Online: 12 March 2021. Р. 137–144.</mixed-citation><mixed-citation xml:lang="en">Drageset J. Health Promotion in Health Care // Vital Theories and Research. First Online: 12 March 2021. Р. 137–144.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Alfonso V., Geller J., Bermbach N. et al. Becoming a «treatment success»: what helps and what hinders patients from achieving and sustaining undetectable viral loads // AIDS Patient Care STDS. 2006. May, Vol. 20, Nо. 5. Р. 326–334. doi: 10.1089/apc.2006.20.326.</mixed-citation><mixed-citation xml:lang="en">Alfonso V., Geller J., Bermbach N. et al. Becoming a «treatment success»: what helps and what hinders patients from achieving and sustaining undetectable viral loads // AIDS Patient Care STDS. 2006. May, Vol. 20, Nо. 5. Р. 326–334. doi: 10.1089/apc.2006.20.326.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Gonzalez J.S., Penedo F.J., Antoni M.H. et al. Social support, positive states of mind, and HIV treatment adherence in men and women living with HIV/AIDS // Health Psychol. 2004. Jul; Vol. 23, Nо. 4. Р. 413–418. doi: 10.1037/0278-6133.23.4.413.</mixed-citation><mixed-citation xml:lang="en">Gonzalez J.S., Penedo F.J., Antoni M.H. et al. Social support, positive states of mind, and HIV treatment adherence in men and women living with HIV/AIDS // Health Psychol. 2004. Jul; Vol. 23, Nо. 4. Р. 413–418. doi: 10.1037/0278-6133.23.4.413.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Fredericksen R.J., Gibbons L.E., Fitzsimmons E. et al. Impact and correlates of sub-optimal social support among patients in HIV care // AIDS Care. 2021 Sep; Vol. 33, Nо. 9. Р. 1178–1188. doi: 10.1080/09540121.2020.1853660.</mixed-citation><mixed-citation xml:lang="en">Fredericksen R.J., Gibbons L.E., Fitzsimmons E. et al. Impact and correlates of sub-optimal social support among patients in HIV care // AIDS Care. 2021 Sep; Vol. 33, Nо. 9. Р. 1178–1188. doi: 10.1080/09540121.2020.1853660.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Zanoni B.C., Archary M., Subramony T. et al. Disclosure, Social Support, and Mental Health are Modifiable Factors Affecting Engagement in Care of Perinatally-HIV Infected Adolescents: A Qualitative Dyadic Analysis // AIDS Behav. 2021. Jan; Vol. 25, Nо. 1. Р. 237–248. doi: 10.1007/s10461-020-02968-1.</mixed-citation><mixed-citation xml:lang="en">Zanoni B.C., Archary M., Subramony T. et al. Disclosure, Social Support, and Mental Health are Modifiable Factors Affecting Engagement in Care of Perinatally-HIV Infected Adolescents: A Qualitative Dyadic Analysis // AIDS Behav. 2021. Jan; Vol. 25, Nо. 1. Р. 237–248. doi: 10.1007/s10461-020-02968-1.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Judd A., Collins I.J., Parrott F. et al. Growing up with perinatal HIV: changes in clinical outcomes before and after transfer to adult care in the UK // J. Int. AIDS Soc. 2017. May 16; Vol. 20, Suppl. 3. Р. 21577. doi: 10.7448/IAS.20.4.21577.</mixed-citation><mixed-citation xml:lang="en">Judd A., Collins I.J., Parrott F. et al. Growing up with perinatal HIV: changes in clinical outcomes before and after transfer to adult care in the UK // J. Int. AIDS Soc. 2017. May 16; Vol. 20, Suppl. 3. Р. 21577. doi: 10.7448/IAS.20.4.21577.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Altice F., Evuarherhe O., Shina S. et al. Adherence to HIV treatment regimens: systematic literature review and meta-analysis // Patient Prefer Adherence. 2019. Vol. 13. Р. 475–490.</mixed-citation><mixed-citation xml:lang="en">Altice F., Evuarherhe O., Shina S. et al. Adherence to HIV treatment regimens: systematic literature review and meta-analysis // Patient Prefer Adherence. 2019. Vol. 13. Р. 475–490.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Cohen J., Beaubrun A., Bashyal R. et al. Real-world adherence and persistence for newly-prescribed HIV treatment: single versus multiple tablet regimen comparison among US medicaid beneficiaries // Comparative Study AIDS Res Ther. 2020. Apr. 1; Vol. 17, Nо. 1. Р. 12. doi: 10.1186/s12981-020-00268-1.</mixed-citation><mixed-citation xml:lang="en">Cohen J., Beaubrun A., Bashyal R. et al. Real-world adherence and persistence for newly-prescribed HIV treatment: single versus multiple tablet regimen comparison among US medicaid beneficiaries // Comparative Study AIDS Res Ther. 2020. Apr. 1; Vol. 17, Nо. 1. Р. 12. doi: 10.1186/s12981-020-00268-1.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
