<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">aids</journal-id><journal-title-group><journal-title xml:lang="ru">ВИЧ-инфекция и иммуносупрессии</journal-title><trans-title-group xml:lang="en"><trans-title>HIV Infection and Immunosuppressive Disorders</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2077-9828</issn><publisher><publisher-name>Baltic Medical Education Center</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22328/2077-9828-2023-15-4-36-46</article-id><article-id custom-type="elpub" pub-id-type="custom">aids-850</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АНАЛИТИЧЕСКИЕ ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ANALYTICAL REVIEWS</subject></subj-group></article-categories><title-group><article-title>Особенности течения менопаузального периода у ВИЧ-инфицированных женщин</article-title><trans-title-group xml:lang="en"><trans-title>Features of menopausal period in HIV-positive women</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1438-2399</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Самарина</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Samarina</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Самарина Анна Валентиновна — доктор медицинских наук, доцент, профессор кафедры социально значимых инфекций и фтизиопульмонологии, Первый Санкт-Петербургский государственный медицинский университет имени академика И. П. Павлова; заведующий отделением материнства и детства, Центр по профилактике и борьбе со СПИД и инфекционными заболеваниями</p><p>190103, Санкт-Петербург, наб. Обводного канала, д. 179</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><email xlink:type="simple">avsamarina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6551-4147</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ярмолинская</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Yarmolinskaya</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ярмолинская Мария Игоревна — доктор медицинских наук, профессор, профессор РАН, заведующий отделом гинекологии и эндокринологии, руководитель центра «Диагностика и лечение эндометриоза</p><p>Researcher ID P-2183–2014; Scopus Author ID: 7801562649</p><p>199034, Санкт-Петербург, Менделеевская линия, д. 3</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><email xlink:type="simple">m.yarmolinskaya@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5200-7672</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колошкина</surname><given-names>A. B.</given-names></name><name name-style="western" xml:lang="en"><surname>Koloshkina</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Колошкина Анастасия Владимировна — ординатор </p><p>199034, Санкт-Петербург, Менделеевская линия, д. 3</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><email xlink:type="simple">nastyasalukhova@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургский Центр по профилактике и борьбе со СПИД и инфекционными заболеваниями; &#13;
Первый Санкт-Петербургский государственный медицинский университет имени академика И. П. Павлова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>St. Petersburg Center for Conrol of AIDS and Infectious Diseases; &#13;
Pavlov First St. Petersburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-исследовательский институт акушерства, гинекологии и репродуктологии имени Д. О. Отта</institution><country>Россия</country></aff><aff xml:lang="en"><institution>The Research Institute of Obstetrics, Gynecology and Reproductology named after D. O. Ott</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>16</day><month>01</month><year>2024</year></pub-date><volume>15</volume><issue>4</issue><fpage>36</fpage><lpage>46</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Самарина А.В., Ярмолинская М.И., Колошкина A.B., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Самарина А.В., Ярмолинская М.И., Колошкина A.B.</copyright-holder><copyright-holder xml:lang="en">Samarina A.V., Yarmolinskaya M.I., Koloshkina A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://hiv.bmoc-spb.ru/jour/article/view/850">https://hiv.bmoc-spb.ru/jour/article/view/850</self-uri><abstract><p>В России доля женщин в структуре ВИЧ-инфицированных пациентов в 2021 г. составила 54,6%. В последние годы в группе женщин, живущих с ВИЧ, отмечается рост числа пациенток старшего репродуктивного возраста, а также тех, кто находится в перии постменопаузе. Данные о возрасте наступления менопаузы и ее течении в рассматриваемой группе женщин противоречивы, а клинические рекомендации по особенностям диспансеризации, выбору антиретровирусной терапии (АРТ) и лечению климактерического синдрома у этой группы пациенток отсутствуют, несмотря на его высокую частоту и большую интенсивность проявлений по сравнению с популяционными показателями. Недостаточное количество исследований на эту тему, низкая информированность врачей о возможностях назначения менопаузальной гормональной терапии (МГТ) пациенткам с ВИЧ и межлекарственных взаимодействиях (МЛВ) МГТ с антиретровирусными препаратами (АРВП) ограничивают оказание эффективной медицинской помощи, ухудшают качество жизни ВИЧ-инфицированных женщин и представляют собой проблему, которая требует решения. В статье предлагается обзор современных исследований, направленных на изучение особенностей течения менопаузы у женщин с ВИЧ, возрастом ее наступления, данных по назначению МГТ. Поиск литературы производился на ресурсе PubMed, в обзор включены статьи, опубликованные в период с 2016 по 2023 г.</p></abstract><trans-abstract xml:lang="en"><p>In 2021 in Russia, the proportion of women among HIV-infected patients was 54.6%. In recent years, there has been an increase in the number of female patients of older reproductive age and those in peri- and postmenopause among women living with HIV. Data on the age of onset of menopause and its course in this group of women are contradictory, and clinical recommendations on the features of dispensary observation, the choice of antiretroviral therapy, and the treatment of climacteric syndrome in this group of patients are absent, despite its high frequency and greater intensity of manifestations compared to population indicators. The insufficient amount of research on this topic, low awareness of doctors about the possibilities of prescribing menopausal hormone therapy to HIV-positive patients, and drug interactions between MHT and antiretroviral drugs limit the provision of effective medical care, worsen the quality of life of HIV-positive women, and represent a problem that requires a solution. This article offers a review of modern studies aimed at studying the peculiarities of menopause in women with HIV, the age of its onset, and data on the prescription of MHT. Literature search was conducted on PubMed, and the review includes articles published from 2016 to 2023.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>менопауза у женщин</kwd><kwd>живущих с ВИЧ</kwd><kwd>симптомы менопаузы</kwd><kwd>менопаузальная гормональная терапия</kwd><kwd>остеопороз у женщин</kwd><kwd>живущих с ВИЧ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>menopause in women living with HIV</kwd><kwd>symptoms of menopause</kwd><kwd>menopausal hormone therapy</kwd><kwd>osteoporosis in women living with HIV</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">ВИЧ-инфекция у взрослых. Клинические национальные рекомендации. 2020.</mixed-citation><mixed-citation xml:lang="en">Clinical national recommendations: HIV infection in adults, 2020  (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Andany N., Kennedy V.L., Aden M., Loutfy M. Perspectives on menopause and women with HIV // Int. J. Womens Health. 2016 Jan 11; Vol. 8. Р. 1–22. doi: 10.2147/IJWH.S62615. PMID: 26834498; PMCID: PMC4716718.</mixed-citation><mixed-citation xml:lang="en">Andany N., Kennedy V.L., Aden M., Loutfy M. Perspectives on menopause and women with HIV // Int. J. Womens Health. 2016 Jan 11; Vol. 8. Р. 1–22. doi: 10.2147/IJWH.S62615. PMID: 26834498; PMCID: PMC4716718.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Глобальная статистика по ВИЧ и СПИД — информационный бюллетень ЮНЭЙДС, 2023</mixed-citation><mixed-citation xml:lang="en">Global statistics on HIV and AIDS — UNAIDS information bulletin, 2023  (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Покровский В.В., Ладная Н.Н., Соколова Е.В. ВИЧ-инфекция за 2021 г. Бюллетень № 47. С. 9</mixed-citation><mixed-citation xml:lang="en">Pokrovsky V.V., Ladnaya N.N., Sokolova E.V. HIV infection for 2021. Bulletin No. 47, р. 9.  (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Виноградова Т.Н., Бембеева Н.А., Пирогова А.В. ВИЧ-инфекция в Санкт-Петербурге по состоянию на 01.07.2023 г. Информационный бюллетень.</mixed-citation><mixed-citation xml:lang="en">Vinogradova T.N., Bembeeva N.A., Pirogova A.V. HIV infection in St. Petersburg as of July 1, 2023. Information bulletin  (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Bull L., Tittle V., Rashid T., Nwokolo N. HIV and the menopause: A review // Post Reprod Health. 2018. Mar; Vol. 24, No. 1. Р. 19–25. doi: 10.1177/2053369117748794. Epub 2017 Dec 17. PMID: 29251186.</mixed-citation><mixed-citation xml:lang="en">Bull L., Tittle V., Rashid T., Nwokolo N. HIV and the menopause: A review // Post Reprod Health. 2018. Mar; Vol. 24, No. 1. Р. 19–25. doi: 10.1177/2053369117748794. Epub 2017 Dec 17. PMID: 29251186.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Smit M., Brinkman K., Geerlings S., Smit C., Thyagarajan K., Sighem Av., de Wolf F., Hallett TB; ATHENA observational cohort. Future challenges for clinical care of an ageing population infected with HIV: a modelling study // Lancet Infect Dis. 2015. Jul; Vol. 15, No. 7. Р. 810–818. doi: 10.1016/S1473-3099(15)00056-0. Epub 2015 Jun 9. Erratum in: Lancet Infect Dis. 2015. Sep; Vol. 15(9. Р. 998. PMID: 26070969; PMCID: PMC4528076.</mixed-citation><mixed-citation xml:lang="en">Smit M., Brinkman K., Geerlings S., Smit C., Thyagarajan K., Sighem Av., de Wolf F., Hallett TB; ATHENA observational cohort. Future challenges for clinical care of an ageing population infected with HIV: a modelling study // Lancet Infect Dis. 2015. Jul; Vol. 15, No. 7. Р. 810–818. doi: 10.1016/S1473-3099(15)00056-0. Epub 2015 Jun 9. Erratum in: Lancet Infect Dis. 2015. Sep; Vol. 15(9. Р. 998. PMID: 26070969; PMCID: PMC4528076.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Sherr L., Molloy A., Macedo A., Croome N., Johnson MA. Ageing and menopause considerations for women with HIV in the UK // Virus Erad. 2016 Oct 5; Vol. 2, No. 4. Р. 215–218. PMID: 27781103; PMCID: PMC5075348.</mixed-citation><mixed-citation xml:lang="en">Sherr L., Molloy A., Macedo A., Croome N., Johnson MA. Ageing and menopause considerations for women with HIV in the UK // Virus Erad.  2016 Oct 5; Vol. 2, No. 4. Р. 215–218. PMID: 27781103; PMCID: PMC5075348.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Tariq S., Burns F.M., Gilson R., Sabin C. PRIME (Positive Transitions Through the Menopause) Study: a protocol for a mixed-methods study investigating the impact of the menopause on the health and well-being of women living with HIV in England // BMJ Open. 2019 Jun 5; Vol. 9, No. 6. Р. e025497. doi: 10.1136/bmjopen-2018-025497. PMID: 31171548; PMCID: PMC6561408.</mixed-citation><mixed-citation xml:lang="en">Tariq S., Burns F.M., Gilson R., Sabin C. PRIME (Positive Transitions Through the Menopause) Study: a protocol for a mixed-methods study investigating the impact of the menopause on the health and well-being of women living with HIV in England // BMJ Open. 2019 Jun 5; Vol. 9, No. 6. Р. e025497. doi: 10.1136/bmjopen-2018-025497. PMID: 31171548; PMCID: PMC6561408.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Ладная Н.Н., Соколова Е.В., Покровский В.В. Основные тенденции развития эпидемии ВИЧ-инфекции среди женщин в Российской Федерации в 2020 году // Актуальные вопросы ВИЧ-инфекции. Охрана здоровья матери и ребенка: международная научно-практическая конференция, Санкт-Петербург, 31 мая — 01 июня 2021 года. СПб.: Санкт-Петербургская общественная организация «Человек и его здоровье», 2021. С. 5–15. EDN UBEPTW.</mixed-citation><mixed-citation xml:lang="en">Ladnaya N.N., Sokolova E.V., Pokrovsky V.V. Main trends in the development of the HIV epidemic among women in the Russian Federation in 2020. Actual issues of HIV infection. Maternal and child health: international scientiﬁc and practical conference, St. Petersburg, May 31 — June 1, 2021. St. Petersburg: St. Petersburg Public Organization «Man and His Health», 2021, рр. 5–15  (In Russ.). EDN UBEPTW.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Chirwa M., Ma R., Guallar C., Tariq S. Managing menopause in women living with HIV: A survey of primary care practitioners // Post Reprod Health. 2017 Sep; Vol. 23, No. 3. Р. 111–115. doi: 10.1177/2053369117712181. Epub 2017 Jun 19. PMID: 28629256; PMCID: PMC5613803.</mixed-citation><mixed-citation xml:lang="en">Chirwa M., Ma R., Guallar C., Tariq S. Managing menopause in women living with HIV: A survey of primary care practitioners // Post Reprod Health. 2017 Sep; Vol. 23, No. 3. Р. 111–115. doi: 10.1177/2053369117712181. Epub 2017 Jun 19. PMID: 28629256; PMCID: PMC5613803.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Менопауза и климактерическое состояние у женщины. Клинические национальные рекомендации. 2021.</mixed-citation><mixed-citation xml:lang="en">Menopause and climacteric state in women. Clinical national recommendation. 2021.  (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Mishra G.D., Chung H.F., Cano A., Chedraui P., Goulis D.G., Lopes P., Mueck A., Rees M., Senturk L.M., Simoncini T., Stevenson J.C., Stute P., Tuomikoski P., Lambrinoudaki I. EMAS position statement: Predictors of premature and early natural menopause // Maturitas. 2019 May; Vol. 123. Р. 82–88. doi: 10.1016/j.maturitas.2019.03.008. Epub 2019 Mar 13. PMID: 31027683.</mixed-citation><mixed-citation xml:lang="en">Mishra G.D., Chung H.F., Cano A., Chedraui P., Goulis D.G., Lopes P., Mueck A., Rees M., Senturk L.M., Simoncini T., Stevenson J.C., Stute P., Tuomikoski P., Lambrinoudaki I. EMAS position statement: Predictors of premature and early natural menopause // Maturitas. 2019 May; Vol. 123. Р. 82–88. doi: 10.1016/j.maturitas.2019.03.008. Epub 2019 Mar 13. PMID: 31027683.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Arinkan S.A., Gunacti M. Factors influencing age at natural menopause // Obstet Gynaecol Res. 2021 Mar; Vol. 47, No. 3. Р. 913–920. doi: 10.1111/jog.14614. Epub 2020 Dec 21. PMID: 33350022.</mixed-citation><mixed-citation xml:lang="en">Arinkan S.A., Gunacti M. Factors inﬂuencing age at natural menopause // Obstet Gynaecol Res. 2021 Mar; Vol. 47, No. 3. Р. 913–920. doi: 10.1111/jog.14614. Epub 2020 Dec 21. PMID: 33350022.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Williams M., Richard-Davis G., Weickert A., Christensen L., Ward E., Schrager S. A review of African American women’s experiences in menopause // Menopause. 2022 Nov 1; Vol. 29, No. 11. Р. 1331–1337. doi: 10.1097/GME.0000000000002060. Epub 2022 Sep 20. PMID: 36126249.</mixed-citation><mixed-citation xml:lang="en">Williams M., Richard-Davis G., Weickert A., Christensen L., Ward E., Schrager S. A review of African American women’s experiences in menopause // Menopause. 2022 Nov 1; Vol. 29, No. 11. Р. 1331–1337. doi: 10.1097/GME.0000000000002060. Epub 2022 Sep 20. PMID: 36126249.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Andany N., Kaida A., de Pokomandy A., Yudin M.H., Wang L., Kennedy V.L., Webster K., Loutfy M; CHIWOS Research Team. Prevalence and correlates of early-onset menopause among women living with HIV in Canada // Menopause. 2020 Jan; Vol. 27, No. 1. Р. 66–75. doi: 10.1097/GME.0000000000001423. PMID: 31688411.</mixed-citation><mixed-citation xml:lang="en">Andany N., Kaida A., de Pokomandy A., Yudin M.H., Wang L., Kennedy V.L., Webster K., Loutfy M; CHIWOS Research Team. Prevalence and correlates of early-onset menopause among women living with HIV in Canada // Menopause. 2020 Jan; Vol. 27, No. 1. Р. 66–75. doi: 10.1097/GME.0000000000001423. PMID: 31688411.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Hachfeld A., Atkinson A., Stute P., Calmy A., Tarr P.E., Darling K.E.A., Babouee Flury B., Polli C., Sultan-Beyer L., Abela I.A., Aebi-Popp K.; Swiss HIV Cohort Study (SHCS). Brief Report: Does Menopause Transition Influence Viral Suppression and Adherence in Women Living With HIV? // Acquir Immune Defic Syndr. 2023 Apr 15; Vol. 92, No. 5. Р. 399–404. doi: 10.1097/QAI.0000000000003158. Epub 2023 Jan 3. PMID: 36595226; PMCID: PMC9988224.</mixed-citation><mixed-citation xml:lang="en">Hachfeld A., Atkinson A., Stute P., Calmy A., Tarr P.E., Darling K.E.A., Babouee Flury B., Polli C., Sultan-Beyer L., Abela I.A., Aebi-Popp K.; Swiss HIV Cohort Study (SHCS). Brief Report: Does Menopause Transition Inﬂuence Viral Suppression and Adherence in Women Living With HIV? // Acquir Immune Deﬁc Syndr. 2023 Apr 15; Vol. 92, No. 5. Р. 399–404. doi: 10.1097/QAI.0000000000003158. Epub 2023 Jan 3. PMID: 36595226; PMCID: PMC9988224.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Sherr L., Molloy A., Macedo A., Croome N., Johnson MA. Ageing and menopause considerations for women with HIV in the UK. // Virus Erad. 2016 Oct 5; Vol. 2, No. 4. Р. 215–218. PMID: 27781103; PMCID: PMC5075348.</mixed-citation><mixed-citation xml:lang="en">Sherr L., Molloy A., Macedo A., Croome N., Johnson MA. Ageing and menopause considerations for women with HIV in the UK. // Virus Erad. 2016 Oct 5; Vol. 2, No. 4. Р. 215–218. PMID: 27781103; PMCID: PMC5075348.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Hachfeld A, Atkinson A, Stute P. et al. Women with HIV transitioning through menopause: Insights from the Swiss HIV Cohort Study (SHCS) // HIV Med. 2022. Vol. 23. Р. 417–425. doi: 10.1111/hiv.13255.</mixed-citation><mixed-citation xml:lang="en">Hachfeld A, Atkinson A, Stute P. et al. Women with HIV transitioning through menopause: Insights from the Swiss HIV Cohort Study (SHCS) // HIV Med. 2022. Vol. 23. Р. 417–425. doi: 10.1111/hiv.13255.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Marincowitz C., Genis A., Goswami N., De Boever P., Nawrot T.S., Strijdom H. Vascular endothelial dysfunction in the wake of HIV and ART //FEBS. 2019 Apr; Vol. 286, No. 7. Р. 1256–1270. doi: 10.1111/febs.14657. Epub 2018 Sep 28. PMID: 30220106.</mixed-citation><mixed-citation xml:lang="en">Marincowitz C., Genis A., Goswami N., De Boever P., Nawrot T.S., Strijdom H. Vascular endothelial dysfunction in the wake of HIV and ART //FEBS. 2019 Apr; Vol. 286, No. 7. Р. 1256–1270. doi: 10.1111/febs.14657. Epub 2018 Sep 28. PMID: 30220106.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Shah A.S.V., Stelzle D., Lee K.K., Beck E.J., Alam S., Clifford S., Longenecker C.T., Strachan F., Bagchi S., Whiteley W., Rajagopalan S., Kottilil S., Nair H., Newby D.E., McAllister D.A., Mills N.L. Global Burden of Atherosclerotic Cardiovascular Disease in People Living With HIV: Systematic Review and Meta-Analysis // Circulation. 2018 Sep 11; Vol. 138, No. 11. Р. 1100–1112. doi: 10.1161/CIRCULATIONAHA.117.033369. PMID: 29967196; PMCID: PMC6221183.</mixed-citation><mixed-citation xml:lang="en">Shah A.S.V., Stelzle D., Lee K.K., Beck E.J., Alam S., Clifford S., Longenecker C.T., Strachan F., Bagchi S., Whiteley W., Rajagopalan S., Kottilil S., Nair H., Newby D.E., McAllister D.A., Mills N.L. Global Burden of Atherosclerotic Cardiovascular Disease in People Living With HIV: Systematic Review and Meta-Analysis // Circulation. 2018 Sep 11; Vol. 138, No. 11. Р. 1100–1112. doi: 10.1161/CIRCULATIONAHA.117.033369. PMID: 29967196; PMCID: PMC6221183.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Alvi R.M., Neilan A.M., Tariq N., Hassan M.O., Awadalla M., Zhang L., Afshar M., Rokicki A., Mulligan C.P., Triant V.A., Zanni M.V., Neilan T.G. The Risk for Sudden Cardiac Death Among Patients Living With Heart Failure and Human Immunodeficiency Virus // JACC Heart Fail. 2019 Sep; Vol. 7, No. 9. Р. 759–767. doi: 10.1016/j.jchf.2019.04.025. Epub 2019 Aug 7. PMID: 31401096; PMCID: PMC6768556.</mixed-citation><mixed-citation xml:lang="en">Alvi R.M., Neilan A.M., Tariq N., Hassan M.O., Awadalla M., Zhang L., Afshar M., Rokicki A., Mulligan C.P., Triant V.A., Zanni M.V., Neilan T.G. The Risk for Sudden Cardiac Death Among Patients Living With Heart Failure and Human Immunodeﬁciency Virus // JACC Heart Fail. 2019 Sep; Vol. 7, No. 9. Р. 759–767. doi: 10.1016/j.jchf.2019.04.025. Epub 2019 Aug 7. PMID: 31401096; PMCID: PMC6768556.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Abelman R.A., Mugo B.M., Zanni M.V. Conceptualizing the Risks of Coronary Heart Disease and Heart Failure Among People Aging with HIV: Sex-Specific Considerations // Curr. Treat Options Cardiovasc. Med. 2019. Jul 15; Vol. 21, No. 8. Р. 41. doi: 10.1007/s11936-019-0744-1. PMID: 31309321.</mixed-citation><mixed-citation xml:lang="en">Abelman R.A., Mugo B.M., Zanni M.V. Conceptualizing the Risks of Coronary Heart Disease and Heart Failure Among People Aging with HIV: Sex-Speciﬁc Considerations // Curr. Treat Options Cardiovasc. Med. 2019. Jul 15; Vol. 21, No. 8. Р. 41. doi: 10.1007/s11936-019-0744-1. PMID: 31309321.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Beckman J.A., Duncan M.S., Alcorn C.W., So-Armah K., Butt A.A., Goetz M.B., Tindle H.A., Sico J.J., Tracy R.P., Justice A.C., Freiberg M.S. Association of Human Immunodeficiency Virus Infection and Risk of Peripheral Artery Disease // Circulation. 2018 Jul 17; Vol. 138, No. 3. Р. 255–265. doi: 10.1161/CIRCULATIONAHA.117.032647. Epub 2018 Mar 13. PMID: 29535090; PMCID: PMC6050082.</mixed-citation><mixed-citation xml:lang="en">Beckman J.A., Duncan M.S., Alcorn C.W., So-Armah K., Butt A.A., Goetz M.B., Tindle H.A., Sico J.J., Tracy R.P., Justice A.C., Freiberg M.S. Association of Human Immunodeﬁciency Virus Infection and Risk of Peripheral Artery Disease // Circulation. 2018 Jul 17; Vol. 138, No. 3. Р. 255–265. doi: 10.1161/CIRCULATIONAHA.117.032647. Epub 2018 Mar 13. PMID: 29535090; PMCID: PMC6050082.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Ebeling P.R., Nguyen H.H., Aleksova J., Vincent A.J., Wong P., Milat F. Secondary Osteoporosis // Endocr. Rev. 2022 Mar 9; Vol. 43 No. 2. Р. 240–313. doi: 10.1210/endrev/bnab028. PMID: 34476488.</mixed-citation><mixed-citation xml:lang="en">Ebeling P.R., Nguyen H.H., Aleksova J., Vincent A.J., Wong P., Milat F. Secondary Osteoporosis // Endocr. Rev. 2022 Mar 9; Vol. 43 No. 2. Р. 240–313. doi: 10.1210/endrev/bnab028. PMID: 34476488.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Negredo E., Warriner A.H. Pharmacologic approaches to the prevention and management of low bone mineral density in HIV-infected patients // Curr. Opin HIV AIDS. 2016 May; Vol. 11, No. 3. Р. 351–357. doi: 10.1097/COH.0000000000000271. PMID: 26890207.</mixed-citation><mixed-citation xml:lang="en">Negredo E., Warriner A.H. Pharmacologic approaches to the prevention and management of low bone mineral density in HIV-infected patients // Curr. Opin HIV AIDS. 2016 May; Vol. 11, No. 3. Р. 351–357. doi: 10.1097/COH.0000000000000271. PMID: 26890207.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Van Ommen C.E., King E.M., Murray M.C.M. Age at menopause in women living with HIV: a systematic review // Menopause. 2021 Dec 1; Vol. 28, No. 12. Р. 1428–1436. doi: 10.1097/GME.0000000000001871. PMID: 34854838.</mixed-citation><mixed-citation xml:lang="en">Van Ommen C.E., King E.M., Murray M.C.M. Age at menopause in women living with HIV: a systematic review // Menopause. 2021 Dec 1; Vol. 28, No. 12. Р. 1428–1436. doi: 10.1097/GME.0000000000001871. PMID: 34854838.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Tariq S., Okhai H., Severn A., Sabin C.A., Burns F., Gilson R., Fox J., Gilleece Y., Mackie N.E., Post F.A., Reeves I., Rosenvinge M., Sullivan A., Ustianowski A., Miller R.F. Follicle-stimulating hormone in postmenopausal women living with HIV: a prevalence study // HIV Med. 2022 Apr; Vol. 23, No. 4. Р. 434–440. doi: 10.1111/hiv.13205. Epub 2021 Nov 17. PMID: 34791781; PMCID: PMC9298721.</mixed-citation><mixed-citation xml:lang="en">Tariq S., Okhai H., Severn A., Sabin C.A., Burns F., Gilson R., Fox J., Gilleece Y., Mackie N.E., Post F.A., Reeves I., Rosenvinge M., Sullivan A., Ustianowski A., Miller R.F. Follicle-stimulating hormone in postmenopausal women living with HIV: a prevalence study // HIV Med. 2022 Apr; Vol. 23, No. 4. Р. 434–440. doi: 10.1111/hiv.13205. Epub 2021 Nov 17. PMID: 34791781; PMCID: PMC9298721.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Prior J.C. Adaptive, reversible, hypothalamic reproductive suppression: More than functional hypothalamic amenorrhea // Front Endocrinol (Lausanne). 2022 Oct 19; Vol. 13. Р. 893889. doi: 10.3389/fendo.2022.893889. PMID: 36339445; PMCID: PMC9626525.</mixed-citation><mixed-citation xml:lang="en">Prior J.C. Adaptive, reversible, hypothalamic reproductive suppression: More than functional hypothalamic amenorrhea // Front Endocrinol (Lausanne). 2022 Oct 19; Vol. 13. Р. 893889. doi: 10.3389/fendo.2022.893889. PMID: 36339445; PMCID: PMC9626525.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">King E.M., Nesbitt A., Albert A.Y.K., Pick N., Cote H.C.F., Maan E.J., Prior J.C., Murray M.C.M.; CIHR team on Cellular Aging and HIV Comorbidities in Women and Children (CARMA). Prolonged Amenorrhea and Low Hip Bone Mineral Density in Women Living With HIV-A Controlled Cross-sectional Study // Acquir Immune Defic Syndr. 2020 Apr 15; Vol. 83, No. 5. Р. 486–495. doi: 10.1097/QAI.0000000000002282. PMID: 31914005.</mixed-citation><mixed-citation xml:lang="en">King E.M., Nesbitt A., Albert A.Y.K., Pick N., Cote H.C.F., Maan E.J., Prior J.C., Murray M.C.M.; CIHR team on Cellular Aging and HIV Comorbidities in Women and Children (CARMA). Prolonged Amenorrhea and Low Hip Bone Mineral Density in Women Living With HIV-A Controlled Cross-sectional Study // Acquir Immune Deﬁc Syndr. 2020 Apr 15; Vol. 83, No. 5. Р. 486–495. doi: 10.1097/QAI.0000000000002282. PMID: 31914005.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Böttcher B., Seeber B., Leyendecker G., Wildt L. Impact of the opioid system on the reproductive axis // Fertil Steril. 2017 Aug; Vol. 1080, No. 2. Р. 207–213. doi: 10.1016/j.fertnstert.2017.06.009. Epub 2017 Jun 29. PMID: 28669481.</mixed-citation><mixed-citation xml:lang="en">Böttcher B., Seeber B., Leyendecker G., Wildt L. Impact of the opioid system on the reproductive axis // Fertil Steril. 2017 Aug; Vol. 1080, No. 2. Р. 207–213. doi: 10.1016/j.fertnstert.2017.06.009. Epub 2017 Jun 29. PMID: 28669481.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Roberts R.E., Farahani L., Webber L., Jayasena C. Current understanding of hypothalamic amenorrhoea // Ther. Adv. Endocrinol Metab. 2020. Jul 30; Vol. 11. Р. 2042018820945854. doi: 10.1177/2042018820945854. PMID: 32843957; PMCID: PMC7418467.</mixed-citation><mixed-citation xml:lang="en">Roberts R.E., Farahani L., Webber L., Jayasena C. Current understanding of hypothalamic amenorrhoea // Ther. Adv. Endocrinol Metab. 2020. Jul 30; Vol. 11. Р. 2042018820945854. doi: 10.1177/2042018820945854. PMID: 32843957; PMCID: PMC7418467.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Prior J.C. Adaptive, reversible, hypothalamic reproductive suppression: More than functional hypothalamic amenorrhea // Front Endocrinol (Lausanne). 2022 Oct 19; Vol. 13. Р. 893889. doi: 10.3389/fendo.2022.893889. PMID: 36339445; PMCID: PMC9626525.</mixed-citation><mixed-citation xml:lang="en">Prior J.C. Adaptive, reversible, hypothalamic reproductive suppression: More than functional hypothalamic amenorrhea // Front Endocrinol (Lausanne). 2022 Oct 19; Vol. 13. Р. 893889. doi: 10.3389/fendo.2022.893889. PMID: 36339445; PMCID: PMC9626525.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Fourman L.T., Fazeli P.K. Neuroendocrine causes of amenorrhea — an update // Clin. Endocrinol. Metab. 2015 Mar; Vol. 100, No. 3. Р. 812– 824. doi: 10.1210/jc.2014-3344. Epub 2015 Jan 12. PMID: 25581597; PMCID: PMC4333037.</mixed-citation><mixed-citation xml:lang="en">Fourman L.T., Fazeli P.K. Neuroendocrine causes of amenorrhea — an update // Clin. Endocrinol. Metab. 2015 Mar; Vol. 100, No. 3. Р. 812– 824. doi: 10.1210/jc.2014-3344. Epub 2015 Jan 12. PMID: 25581597; PMCID: PMC4333037.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Cejtin H.E., Evans C.T., Greenblatt R., Minkoff H., Weber K.M., Wright R., Colie C., Golub E., Massad L.S. Prolonged Amenorrhea and Resumption of Menses in Women with HIV // Womens Health (Larchmt). 2018 Sep 14; Vol. 27, No. 12. Р. 1441–1448. doi: 10.1089/jwh.2018.7046. Epub ahead of print. PMID: 30222490; PMCID: PMC6306666.</mixed-citation><mixed-citation xml:lang="en">Cejtin H.E., Evans C.T., Greenblatt R., Minkoff H., Weber K.M., Wright R., Colie C., Golub E., Massad L.S. Prolonged Amenorrhea and Resumption of Menses in Women with HIV // Womens Health (Larchmt). 2018 Sep 14; Vol. 27, No. 12. Р. 1441–1448. doi: 10.1089/jwh.2018.7046. Epub ahead of print. PMID: 30222490; PMCID: PMC6306666.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Sarri G., Pedder H., Dias S., Guo Y., Lumsden M.A. Vasomotor symptoms resulting from natural menopause: a systematic review and network meta-analysis of treatment effects from the National Institute for Health and Care Excellence guideline on menopause // BJOG. 2017 Sep; Vol. 124, No. 10. Р. 1514–1523. doi: 10.1111/1471-0528.14619. Epub 2017 May 11. PMID: 28276200.</mixed-citation><mixed-citation xml:lang="en">Sarri G., Pedder H., Dias S., Guo Y., Lumsden M.A. Vasomotor symptoms resulting from natural menopause: a systematic review and network meta-analysis of treatment effects from the National Institute for Health and Care Excellence guideline on menopause // BJOG. 2017 Sep; Vol. 124, No. 10. Р. 1514–1523. doi: 10.1111/1471-0528.14619. Epub 2017 May 11. PMID: 28276200.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Ярмолинская М.И., Татарова Н.А., Касян В.Н., Петросян А.С. Эффективность негормональной терапии в лечении женщин с климактерическим синдромом // Российский вестник акушера-гинеколога. 2021. Т. 21, № 2. Р. 91–101. doi.org/10.17116/rosakush20212102191.</mixed-citation><mixed-citation xml:lang="en">Yarmolinskaya M.I., Tatarova N.A., Kasyan V.N., Petrosyan A.S. Effi of non-hormonal therapy for menopausal syndrome treatment. Russian Bulletin of ObstetricianGynecologist, 2021, Vol. 21, No. 2, рр. 91–101  (In Russ.). doi.org/10.17116/rosakush20212102191.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Dragovic B., Rymer J, Nwokolo N. Menopause care in women living with HIV in the UK — A review // Virus Erad. 2022. Feb 15; Vol. 8, No. 1. Р. 100064. doi: 10.1016/j.jve.2022.100064. PMID: 35242357; PMCID: PMC8866072.</mixed-citation><mixed-citation xml:lang="en">Dragovic B., Rymer J, Nwokolo N. Menopause care in women living with HIV in the UK — A review // Virus Erad. 2022. Feb 15; Vol. 8, No. 1. Р. 100064. doi: 10.1016/j.jve.2022.100064. PMID: 35242357; PMCID: PMC8866072.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Ryom L., De Miguel R., Cotter A.G., Podlekareva D., Beguelin C., Waalewijn H., Arribas J.R., Mallon P.W.G., Marzolini C., Kirk O., Bamford A., Rauch A., Molina J.M., Kowalska J.D., Guaraldi G., Winston A., Boesecke C., Cinque P., Welch S., Collins S., Behrens G.M.N.; EACS Governing Board. Major revision version 11.0 of the European AIDS Clinical Society Guidelines 2021 // HIV Med. 2022 Sep; Vol. 23, No. 8. Р. 849–858. doi: 10.1111/hiv.13268. Epub 2022 Mar 25. PMID: 35338549; PMCID: PMC9545286.</mixed-citation><mixed-citation xml:lang="en">Ryom L., De Miguel R., Cotter A.G., Podlekareva D., Beguelin C., Waalewijn H., Arribas J.R., Mallon P.W.G., Marzolini C., Kirk O., Bamford A., Rauch A., Molina J.M., Kowalska J.D., Guaraldi G., Winston A., Boesecke C., Cinque P., Welch S., Collins S., Behrens G.M.N.; EACS Governing Board. Major revision version 11.0 of the European AIDS Clinical Society Guidelines 2021 // HIV Med. 2022 Sep; Vol. 23, No. 8. Р. 849–858. doi: 10.1111/hiv.13268. Epub 2022 Mar 25. PMID: 35338549; PMCID: PMC9545286.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Chang C.J., Chan Y.L., Pramukti I., Ko N.Y., Tai T.W. People with HIV infection had lower bone mineral density and increased fracture risk: a meta-analysis // Arch. Osteoporos. 2021 Feb 27; Vol. 16, No. 1. Р. 47. doi: 10.1007/s11657-021-00903-y. PMID: 33638754.</mixed-citation><mixed-citation xml:lang="en">Chang C.J., Chan Y.L., Pramukti I., Ko N.Y., Tai T.W. People with HIV infection had lower bone mineral density and increased fracture risk: a meta-analysis // Arch. Osteoporos. 2021 Feb 27; Vol. 16, No. 1. Р. 47. doi: 10.1007/s11657-021-00903-y. PMID: 33638754.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Finnerty F., Walker-Bone K., Tariq S. Osteoporosis in postmenopausal women living with HIV // Maturitas. 2017. Jan; Vol. 95. Р. 50–54. doi: 10.1016/j.maturitas.2016.10.015. Epub 2016 Nov 5. PMID: 27889053; PMCID: PMC5363814.</mixed-citation><mixed-citation xml:lang="en">Finnerty F., Walker-Bone K., Tariq S. Osteoporosis in postmenopausal women living with HIV // Maturitas. 2017. Jan; Vol. 95. Р. 50–54. doi: 10.1016/j.maturitas.2016.10.015. Epub 2016 Nov 5. PMID: 27889053; PMCID: PMC5363814.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Cabrera D.M., Cornejo M.P., Slotkin R., Pinedo Y., Yu W., Guan W., Garcia P.J., Hsieh E. Prevalence of and risk factors for vertebral fracture and low bone mineral density among Peruvian women aging with HIV // Arch Osteoporos. 2023. May 10; Vol. 18, No. 1. Р. 64. doi: 10.1007/s11657-023-01250-w. PMID: 37160770; PMCID: PMC10170032.</mixed-citation><mixed-citation xml:lang="en">Cabrera D.M., Cornejo M.P., Slotkin R., Pinedo Y., Yu W., Guan W., Garcia P.J., Hsieh E. Prevalence of and risk factors for vertebral fracture and low bone mineral density among Peruvian women aging with HIV // Arch Osteoporos. 2023. May 10; Vol. 18, No. 1. Р. 64. doi: 10.1007/s11657-023-01250-w. PMID: 37160770; PMCID: PMC10170032.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Marincowitz C., Genis A., Goswami N., De Boever P, Nawrot T.S., Strijdom H. Vascular endothelial dysfunction in the wake of HIV and ART // FEBS. 2019 Apr; Vol. 286, No. 7. Р. 1256–1270. doi: 10.1111/febs.14657. Epub 2018 Sep 28. PMID: 30220106.</mixed-citation><mixed-citation xml:lang="en">Marincowitz C., Genis A., Goswami N., De Boever P, Nawrot T.S., Strijdom H. Vascular endothelial dysfunction in the wake of HIV and ART // FEBS. 2019 Apr; Vol. 286, No. 7. Р. 1256–1270. doi: 10.1111/febs.14657. Epub 2018 Sep 28. PMID: 30220106.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Hoy J.F., Grund B., Roediger M., Schwartz A.V., Shepherd J., Avihingsanon A., Badal-Faesen S., de Wit S., Jacoby S., La Rosa A., Pujari S., Schechter M., White D., Engen N.W., Ensrud K., Aagaard P.D., Carr A.; INSIGHT START Bone Mineral Density Substudy Group. Immediate Initiation of Antiretroviral Therapy for HIV Infection Accelerates Bone Loss Relative to Deferring Therapy: Findings from the START Bone Mineral Density Substudy, a Randomized Trial // Bone Miner Res. 2017 Sep; Vol. 32, No. 9. Р. 1945–1955. doi: 10.1002/jbmr.3183. Epub 2017 Jun 26. PMID: 28650589; PMCID: PMC5555813.</mixed-citation><mixed-citation xml:lang="en">Hoy J.F., Grund B., Roediger M., Schwartz A.V., Shepherd J., Avihingsanon A., Badal-Faesen S., de Wit S., Jacoby S., La Rosa A., Pujari S., Schechter M., White D., Engen N.W., Ensrud K., Aagaard P.D., Carr A.; INSIGHT START Bone Mineral Density Substudy Group. Immediate Initiation of Antiretroviral Therapy for HIV Infection Accelerates Bone Loss Relative to Deferring Therapy: Findings from the START Bone Mineral Density Substudy, a Randomized Trial // Bone Miner Res. 2017 Sep; Vol. 32, No. 9. Р. 1945–1955. doi: 10.1002/jbmr.3183. Epub 2017 Jun 26. PMID: 28650589; PMCID: PMC5555813.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Biver E. Osteoporosis and HIV Infection // Calcif Tissue Int. 2022. May; Vol. 110, No. 5. Р. 624–640. doi: 10.1007/s00223-022-00946-4. Epub 2022 Jan 30. PMID: 35098324; PMCID: PMC9013331.</mixed-citation><mixed-citation xml:lang="en">Biver E. Osteoporosis and HIV Infection // Calcif Tissue Int. 2022. May; Vol. 110, No. 5. Р. 624–640. doi: 10.1007/s00223-022-00946-4. Epub 2022 Jan 30. PMID: 35098324; PMCID: PMC9013331.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Chirwa M., Taghinejadi N., Macaulay G., Mandalia S., Bellone C., Panay N., Brum R., Nwokolo N. Reflections on a specialist HIV menopause service: Experiences of managing menopause in women living with HIV: Experiences of managing menopause in women living with HIV // HIV Med. 2022 Apr; Vol. 23, No. 4. Р. 426–433. doi: 10.1111/hiv.13256. PMID: 35249262.</mixed-citation><mixed-citation xml:lang="en">Chirwa M., Taghinejadi N., Macaulay G., Mandalia S., Bellone C., Panay N., Brum R., Nwokolo N. Reﬂections on a specialist HIV menopause service: Experiences of managing menopause in women living with HIV: Experiences of managing menopause in women living with HIV // HIV Med. 2022 Apr; Vol. 23, No. 4. Р. 426–433. doi: 10.1111/hiv.13256. PMID: 35249262.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Tittle V., Bull L., Boffito M., Nwokolo N. Pharmacokinetic and pharmacodynamic drug interactions between antiretrovirals and oral contraceptives // Clin. Pharmacokinet. 2015 Jan; Vol. 54, No. 1. Р. 23–34. doi: 10.1007/s40262–014–0204–8. PMID: 25331712.</mixed-citation><mixed-citation xml:lang="en">Tittle V., Bull L., Boffito M., Nwokolo N. Pharmacokinetic and pharmacodynamic drug interactions between antiretrovirals and oral contraceptives // Clin. Pharmacokinet. 2015 Jan; Vol. 54, No. 1. Р. 23–34. doi: 10.1007/s40262–014–0204–8. PMID: 25331712.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Santoro N., Roeca C., Peters B.A., Neal-Perry G. The Menopause Transition: Signs, Symptoms, and Management Options // Clin. Endocrinol. Metab. 2021. Jan 1; Vol. 106, No. 1. Р. 1–15. doi: 10.1210/clinem/dgaa764. PMID: 33095879.</mixed-citation><mixed-citation xml:lang="en">Santoro N., Roeca C., Peters B.A., Neal-Perry G. The Menopause Transition: Signs, Symptoms, and Management Options // Clin. Endocrinol. Metab. 2021. Jan 1; Vol. 106, No. 1. Р. 1–15. doi: 10.1210/clinem/dgaa764. PMID: 33095879.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Solomon D., Sabin C.A., Burns F., Gilson R., Allan S., de Ruiter A., Dhairyawan R., Fox J., Gilleece Y., Jones R., Post F., Reeves I., Ross J., Ustianowski A., Shepherd J., Tariq S. The association between severe menopausal symptoms and engagement with HIV care and treatment in women living with HIV // AIDS Care. 2021 Jan; Vol. 33, No. 1. Р. 101–108. doi: 10.1080/09540121.2020.1748559. Epub 2020 Apr 11. PMID: 32279528; PMCID: PMC8043570.</mixed-citation><mixed-citation xml:lang="en">Solomon D., Sabin C.A., Burns F., Gilson R., Allan S., de Ruiter A., Dhairyawan R., Fox J., Gilleece Y., Jones R., Post F., Reeves I., Ross J., Ustianowski A., Shepherd J., Tariq S. The association between severe menopausal symptoms and engagement with HIV care and treatment in women living with HIV // AIDS Care. 2021 Jan; Vol. 33, No. 1. Р. 101–108. doi: 10.1080/09540121.2020.1748559. Epub 2020 Apr 11. PMID: 32279528; PMCID: PMC8043570.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Hamoda H., Panay N., Pedder H., Arya R., Savvas M. The British Menopause Society &amp; Women’s Health Concern 2020 recommendations on hormone replacement therapy in menopausal women // Post. Reprod Health. 2020. Dec; Vol. 26, No. 4. Р. 181–209. doi: 10.1177/2053369120957514. Epub 2020 Oct 12. PMID: 33045914.</mixed-citation><mixed-citation xml:lang="en">Hamoda H., Panay N., Pedder H., Arya R., Savvas M. The British Menopause Society &amp; Women’s Health Concern 2020 recommendations on hormone replacement therapy in menopausal women // Post. Reprod Health. 2020. Dec; Vol. 26, No. 4. Р. 181–209. doi: 10.1177/2053369120957514. Epub 2020 Oct 12. PMID: 33045914.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
