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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">aids</journal-id><journal-title-group><journal-title xml:lang="ru">ВИЧ-инфекция и иммуносупрессии</journal-title><trans-title-group xml:lang="en"><trans-title>HIV Infection and Immunosuppressive Disorders</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2077-9828</issn><publisher><publisher-name>Baltic Medical Education Center</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.22328/2077-9828-2015-7-3-24-33</article-id><article-id custom-type="elpub" pub-id-type="custom">aids-93</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group></article-categories><title-group><article-title>ОППОРТУНИСТИЧЕСКИЕ ИНФЕКЦИИ НЕБАКТЕРИАЛЬНОЙ ПРИРОДЫ КАК ПРИЧИНА ЛЕТАЛЬНЫХ ИСХОДОВ У ВИЧ-ИНФИЦИРОВАННЫХ ПАЦИЕНТОВ. Часть I. ЦИТОМЕГАЛОВИРУСНАЯ ИНФЕКЦИЯ, ТОКСОПЛАЗМОЗ</article-title><trans-title-group xml:lang="en"><trans-title>OPPORTUNISTIC INFECTIONS NONBAKTERIAL NATURE AS THE CAUSE OF DEATH IN HIV-INFECTED PATIENTS.PART I. CITOMEGALOVIRAL INFECTION, TOXOPLASMOSIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акинфиев</surname><given-names>Илья Борисович</given-names></name><name name-style="western" xml:lang="en"><surname>Akinfiev</surname><given-names>I. B.</given-names></name></name-alternatives><email xlink:type="simple">akinfievib@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кубрак</surname><given-names>Дарья Николаевна</given-names></name><name name-style="western" xml:lang="en"><surname>Kubrak</surname><given-names>D. N.</given-names></name></name-alternatives><email xlink:type="simple">darya-kubrak@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Балмасова</surname><given-names>Ирина Петровна</given-names></name><name name-style="western" xml:lang="en"><surname>Balmasova</surname><given-names>I. P.</given-names></name></name-alternatives><email xlink:type="simple">iri.balm@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шестакова</surname><given-names>Ирина Викторовна</given-names></name><name name-style="western" xml:lang="en"><surname>Shestakova</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">prof.shestakova@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ющук</surname><given-names>Николай Дмитриевич</given-names></name><name name-style="western" xml:lang="en"><surname>Yushchuk</surname><given-names>N. D.</given-names></name></name-alternatives><email xlink:type="simple">prof.uyshuk@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБОУ ВПО МГМСУ им. А.И. Евдокимова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow State University of Medcine &amp; Dentistry named by A.I. Evdokimov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2015</year></pub-date><volume>7</volume><issue>3</issue><fpage>24</fpage><lpage>33</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Акинфиев И.Б., Кубрак Д.Н., Балмасова И.П., Шестакова И.В., Ющук Н.Д., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Акинфиев И.Б., Кубрак Д.Н., Балмасова И.П., Шестакова И.В., Ющук Н.Д.</copyright-holder><copyright-holder xml:lang="en">Akinfiev I.B., Kubrak D.N., Balmasova I.P., Shestakova I.V., Yushchuk N.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://hiv.bmoc-spb.ru/jour/article/view/93">https://hiv.bmoc-spb.ru/jour/article/view/93</self-uri><abstract><p>Обзор содержит анализ данных литературы, посвященных актуальной проблеме развития наиболее часто регистрируемых оппортунистических инфекций небактериальной природы (вирусной, протозойной, грибковой) и обусловленных ими летальных исходов у больных с ВИЧ/СПИД. Часть I содержит сведения об оппортунистическом характере цитомегаловирусной инфекции и токсоплазмоза, при этом дается характеристика особенностей развития и течения названных инфекций у больных с ВИЧ/СПИД, их иммунопатогенеза и наиболее частых клинических проявлений, обозначаются основные причины и факторы риска летальных исходов, возможность влияния на них сопутствующих инфекционных процессов, приемы лабораторной диагностики. В первой части статьи подчеркивается недостаточная изученность проблемы прогнозирования летальных исходов при цитомегаловирусной инфекции и токсоплазмозе, как и необходимость ее дальнейшего решения.</p></abstract><trans-abstract xml:lang="en"><p>This survey contains the data analysis of literature, that is devoted to the urgent problem of development of the most commonly registered nonbacterial opportunistic infections (viral, fungal, protozoal) and their resulting deaths of the HIV/AIDS patients. The first part contains information about opportunistic nature of cytomegalovirus infection and toxoplasmosis, while the development and course of the mentioned infections of patients with HIV/AIDS, their immunopathogenesis and the most frequent clinical manifestations are given too. There are also mentioned the reasons and risk factors of deaths, the ability to influence them of accompanying infectious processes. Moreover, there is possible to see the methods of laboratory diagnostics. At the conclusion of the first part of the article, the lack of knowledge about the problems of forecasting deaths with сytomegalovirus infection and toxoplasmosis, as well as the need for further action are being highlighted.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>токсоплазиоз</kwd><kwd>цитомегаловирусы</kwd><kwd>иммунодефицит</kwd><kwd>toxoplasmosis</kwd><kwd>cytomegalovirus</kwd><kwd>immunodeficiency</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ермак Т.Н., Кравченко А.В., Груздев Б.М. Вторичные заболевания у больных ВИЧ-инфекцией - 15-летнее наблюдение // Тер. архив. - 2004. - Т. 76. - С. 18-20</mixed-citation><mixed-citation xml:lang="en">Ермак Т.Н., Кравченко А.В., Груздев Б.М. 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