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CASE REPORT ABOUT SUCCESSFUL HIV PREVENTION AFTER TRANSFUSION OF HIV-INFECTED ERYTHROCYTE SUSPENSION

https://doi.org/10.22328/2077-9828-2015-7-3-87-96

Abstract

A unique clinical case of successful prevention of HIV infection after transfusion of erythrocyte suspension contaminated with HIV to a 1-year child is described. Importantly, the condition of the child being transfused was severely bad after abdominal operation complicated with intoxication, severe anemia, postoperative bowel syndrome, and sepsis. All this in combination with the high level of HIV RNA in donated blood (more than 40 000 copies per 1 mL) made the risk of HIV transmission very high. The absence of an established procedure for preventive interventions under such conditions and a limited published experience of dealing with such cases made the management of this case still more complicated. The clinical tactics discussed in the present paper resulted in the positive dynamics of laboratory tests and thus may be useful for scholars and clinicians.

About the Authors

A. V. Samarina
Saint-Petersburg Center for Control of AIDS and Infectious Diseases; First Pavlov State Medical University of Saint-Petersburg
Russian Federation


Ye. B. Yastrebova
Saint-Petersburg Center for Control of AIDS and Infectious Diseases; First Pavlov State Medical University of Saint-Petersburg
Russian Federation


Z. N. Lisitsyna
Saint-Petersburg Center for Control of AIDS and Infectious Diseases; First Pavlov State Medical University of Saint-Petersburg
Russian Federation


N. Ye. Dement’Yeva
Saint-Petersburg Center for Control of AIDS and Infectious Diseases; Institute of Experimental Medicine
Russian Federation


Ye. N. Voropayeva
Saint-Petersburg Center for Control of AIDS and Infectious Diseases
Russian Federation


N. V. Sizova
Saint-Petersburg Center for Control of AIDS and Infectious Diseases; First Pavlov State Medical University of Saint-Petersburg
Russian Federation


V. V. Rassokhin
Saint-Petersburg Center for Control of AIDS and Infectious Diseases; First Pavlov State Medical University of Saint-Petersburg
Russian Federation


O. V. Panteleyeva
Saint-Petersburg Center for Control of AIDS and Infectious Diseases
Russian Federation


O. V. Koltsova
Saint-Petersburg Center for Control of AIDS and Infectious Diseases
Russian Federation


I. A. Abramova
Saint-Petersburg Center for Control of AIDS and Infectious Diseases
Russian Federation


A. V. Dmitriyev
Institute of Experimental Medicine
Russian Federation


N. A. Belyakov
Saint-Petersburg Center for Control of AIDS and Infectious Diseases; First Pavlov State Medical University of Saint-Petersburg
Russian Federation


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Review

For citations:


Samarina A.V., Yastrebova Ye.B., Lisitsyna Z.N., Dement’Yeva N.Ye., Voropayeva Ye.N., Sizova N.V., Rassokhin V.V., Panteleyeva O.V., Koltsova O.V., Abramova I.A., Dmitriyev A.V., Belyakov N.A. CASE REPORT ABOUT SUCCESSFUL HIV PREVENTION AFTER TRANSFUSION OF HIV-INFECTED ERYTHROCYTE SUSPENSION. HIV Infection and Immunosuppressive Disorders. 2015;7(3):87-96. (In Russ.) https://doi.org/10.22328/2077-9828-2015-7-3-87-96

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