CHRONIC VIRAL HEPATITIS IN THE NORTHWEST FEDERAL REGION OF RUSSIA
https://doi.org/10.22328/2077-9828-2017-9-2-74-81
Abstract
Study objective: To characterize chronic viral hepatitis C epidemic in the districts of the Northwest Federal Region and in the region as a whole. Materials and methods: Analysis of state statistics about infectious diseases in the Russian Federation as presented in Form No. 1 «Information on Infectious and Invasion Diseases» and in statistical tables developed at Methodological and Research Canter for Epidemiological Surveillance of Viral Hepatitis under Pasteur Institute of Epidemiology and Microbiology. Results: In 1996–2006, chronic hepatitis C incidence in the Northwest Federal Region was several times higher than in the Russian Federation on average. The minimum and maximum rates of newly found hepatitis C cases were 17,2о/оооо in Pskov Oblast and 93,5о/оооо in Saint Petersburg. The highest prevalence levels in all districts and in the whole region were found in the age group of 20 to 49 years. Hepatitis C prevalence in the Northwest Region is 1,7 times higher than in the Russian Federation on average (680,2о/оооо vs. 388,8о/оооо). In the year 2015 compared with 2014, the proportion of diagnoses confirmed with serological and molecular biological tests increased from 35,6 to 81,2%. However, in Leningrad Oblast, the proportion of diagnoses based solely on blood HVC antibodies increased from 57,5% to 73,1%. In Karelia, molecular biological tests were not used in 100% of cases. Conclusion: The high number of hepatitis C patients who may produce new HVC cases warrants strict registering and outpatient follow-up of infected persons and people who contacts with them at specialized clinics. The involvement of young and middle age people in HVC epidemic is prone with the formation of a population having liver cirrhosis and hepatocellular carcinoma, which makes it expedient to develop programs of antiviral therapy aimed at preventing the unfavorable outcomes of chronic viral hepatitis.
About the Authors
Ye. V. Esaulenko
Saint-Petersburg Pasteur Institute;
Saint-Petersburg State Pediatric Medical University.
Russian Federation
Russian Federation
A. A. Sukhoruk
Saint-Petersburg Pasteur Institute;
Saint-Petersburg State Pediatric Medical University.
Russian Federation
Russian Federation
M. V. Poniatishina
Saint-Petersburg Pasteur Institute;
Saint-Petersburg State Pediatric Medical University.
Russian Federation
Russian Federation
R. A. Ganchenko
ФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет» МЗ РФ.
Russian Federation
Russian Federation
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Review
For citations:
Esaulenko Ye.V., Sukhoruk A.A., Poniatishina M.V., Ganchenko R.A. CHRONIC VIRAL HEPATITIS IN THE NORTHWEST FEDERAL REGION OF RUSSIA. HIV Infection and Immunosuppressive Disorders. 2017;9(2):74-81. (In Russ.) https://doi.org/10.22328/2077-9828-2017-9-2-74-81
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