Preview

ВИЧ-инфекция и иммуносупрессии

Расширенный поиск

МУЛЬТИДИСЦИПЛИНАРНЫЙ ПОДХОД К ПРОФИЛАКТИКЕ ИНФЕКЦИЙ, ПЕРЕДАВАЕМЫХ ПОЛОВЫМ ПУТЕМ, И ГЕМОКОНТАКТНЫХ ИНФЕКЦИЙ

https://doi.org/10.22328/2077-9828-2018-10-4-100-112

Полный текст:

Аннотация

Общая методология профилактики инфекций, передаваемых половым путем (ИППП), включая ВИЧ-инфекцию, и гемоконтактных инфекций (ГКИ) до последнего времени в России практически не разрабатывалась, а адресные превентивные вмешательства (интервенции), направленные на уязвимые группы населения, не применялись. Как правило, отечественные исследователи ограничивались анализом эпидемиологических данных о распространенности ИППП и других социально-значимых заболеваний в общей популяции, их клинических особенностей, не предлагая форм и технологий социальной профилактики. Тем временем во всем мире выполняется огромное количество научных исследований, направленных на совершенствование стратегий профилактики ИППП/ГКИ, апробируются комплексные превентивные программы, сочетающие в себе биомедицинские и поведенческие компоненты. К сожалению, разработанные за рубежом профилактические программы не могут быть механически внедрены в практику российского здравоохранения. Они должны быть адаптированы и реализовываться в контексте социально-экономических и культурных особенностей нашей страны. Современная эпидемическая ситуация настоятельно диктует необходимость перехода от вторичной и третичной профилактики ИППП/ГКИ к первичной и от традиционного биомедицинского подхода — к мультидисциплинарному. Мультидисциплинарный подход к формированию здорового образа жизни и предупреждению саморазрушающего поведения, включая употребление алкоголя и наркотиков и рискованные сексуальные отношения,— это новое направление медицинской науки. Статья посвящена анализу теоретико-методологических и практических аспектов разработки, внедрения и оценки эффективности превентивных поведенческих интервенций в сфере социально-значимых инфекций.

Об авторах

Т. В. Красносельских
ФГБОУ ВО «Первый Санкт-Петербургский государственный медицинский университет имени академика И.П.Павлова» МЗ РФ
Россия

Красносельских Татьяна Валерьевна — д.м.н., профессор кафедры дерматовенерологии с клиникой 

19022 Санкт-Петербург, ул. Льва Толстого, 6–8, корп. 4



А. В. Шаболтас
ФГБОУ ВО «Санкт-Петербургский государственный университет»
Россия

Шаболтас Алла Вадимовна — к.п.н., зав. кафедрой психологии здоровья и отклоняющегося поведения факультета психологии 

199034, Санкт-Петербург, Университетская наб., 7/9



Список литературы

1. Singer M., Baer H. Critical medical anthropology. Amiytyville, New York: Baywood Publishing Co., 1995, 406 р.

2. Михель Д.В. Социальная антропология медицинских систем: медицинская антропология. Cаратов: Новый проект, 2010. 80 с. [Michel D.V. Social anthropology of medical systems: medical anthropology. Saratov: New Project, 2010, 80 p. (In Russ.)].

3. Singer M., Clair S. Syndemics and public health: reconceptualizing disease in bio-social context. Med. Anthropol. Q., 2003, Vol. 17, No. 4, pp. 423–441.

4. Singer M. Pathogen-pathogen interaction: a syndemic model of complex biosocial processes in disease. Virulence, 2010, Vol. 1, No. 1, pp. 10–18.

5. Castro A., Farmer P. Infectious disease in Haiti. HIV/AIDS, tuberculosis and social inequalities. EMBO Rep., 2003, Vol. 4, Spec. No., pp. 20–23.

6. Castro A., Farmer P. Medical anthropology in the United States. In: Medical anthropology: regional perspectives and shared concerns. Eds. S.Genest, F.Saillant. Malden, Ma: Blackwell Publishing, 2007, 305 p. (pp. 42–57).

7. Макарова Л.П. Методологические основы превентологии (профилактика социальных отклонений // Известия РГПУ им. А.И.Герцена. 2012. № 145. С. 44–54 [Makarova L.P. The methodological bases of preventology (prophylaxis of social deviations). Izvestiya: Herzen University Journal of Humanities & Science, 2012, No. 145, pp. 44–54 (In Russ.)].

8. Manhart L.E., Holmes K.K. Randomized controlled trials of individual-level, population-level, and multilevel interventions for preventing sexually transmitted infections: what has worked? J. Infect. Dis., 2005, Vol. 191, Suppl. 1, pp. S7–S24.

9. Charania M.R., Crepaz N., Guenther-Gray C. et al. Efficacy of structural-level condom distribution interventions: a meta-analysis of U.S. and international studies, 1998–2007. AIDS Behav., 2011, Vol. 15, No. 7, pp. 1283–1297.

10. Piper J.M. Prevention of sexually transmitted infections in women. Infect. Dis. Clin. North Am., 2008, Vol. 22, No. 4, pp. 619–635.

11. Wetmore C.M., Manhart L.E., Wasserheit J.N. Randomized controlled trials of interventions to prevent sexually transmitted infections: learning from the past to plan for the future. Epidemiol. Rev., 2010, Vol. 32, No. 1, pp. 121–136.

12. Скочилов Р.В. Модели «социального сопровождения» в мировой практике // Русский журнал СПИД, рак и общественное здоровье. 2010. T. 14, № 1. C. 75–77 [Skochilov R.V. The models of social follow-up in the world’s practice. Russian Journal AIDS, Cancer and Public Health, 2010, Vol. 14, No. 1, pp. 75–77 (In Russ.)].

13. Gribble J.N., Miller H.G., Rogers S.M., Turner C.F. Interview mode and measurement of sexual behaviors: methodological issues. J. Sex. Res., 1999, Vol. 36, No. 1, pp. 16–24.

14. Solomon J., Card J.J., Malow R.M. Adapting efficacious interventions: advancing translational research in HIV prevention. Eval. Health Prof., 2006, Vol. 29, No. 2, pp. 162–194.

15. May R.M., Anderson R.M. Transmission dynamics of HIV infection. Nature, 1987, Vol. 326, No. 6109, pp. 137–142.

16. Anderson R.M. The transmission dynamics of sexually transmitted diseases: the behavioral component. In: Research issues in human behavior and sexually transmitted diseases in the AIDS era. Eds. J.N.Wasserheit, S.O.Aral, K.K.Holmes, P.J.Hitchcock. Washington, D.C.: American Society for Microbiology, 1991, 401 p. (pp. 38–60).

17. Aral S.O. Determinants of STD epidemics: implications for phase appropriate intervention strategies. Sex. Transm. Infect., 2002, Vol. 78, Suppl. 1, pp. i3–i13.

18. Da Ros C.T., Schmitt C.S. Global epidemiology of sexually transmitted diseases. Asian J. Androl., 2008, Vol. 10, No. 1, pp. 110–114.

19. Korenromp E.L., White R.G., Orroth K.K. et al. Determinants of the impact of sexually transmitted infection treatment on prevention of HIV infection: a synthesis of evidence from the Mwanza, Rakai, and Masaka intervention trials. J. Infect. Dis., 2005, Vol. 191, Suppl. 1, pp. 168–178.

20. Fawole O.I., Okesola A.O., Fawole A.O. Genital ulcers disease among sexually transmitted disease clinic attendees in Ibadan, Nigeria. Afr. J. Med. Sci., 2000, Vol. 29, No. 1, pp. 17–22.

21. Grosskurth Н. From Mwanza and Rakai to Beijing and Moscow? STD control and HIV prevention. Sex. Transm. Infect., 1999, Vol. 75, No. 2, pp. 83–85.

22. Cohen M.S., Hoffmann I.F., Royce R.A. et al. Reduction of concentration of HIV-1 in semen after treatment of urethritis: implications for prevention of sexual transmission of HIV-1. AIDSCAP Malawi Research Group. Lancet, 1997, Vol. 349, No. 9069, pp. 1868–1873.

23. Corey L., Wald A., Celum C.L., Quinn T.C. The effects of herpes simplex virus-2 on HIV-1 acquisition and transmission: a review of two overlapping epidemics. J. Acquir. Immune Defic. Syndr., 2004, Vol. 35, No. 5, pp. 435–445.

24. Chakraborty H., Sen P.K., Helms R.W. et al. Viral burden in genital secretions determines male-to-female sexual transmission of HIV-1: a probabilistic empiric model. AIDS, 2001, Vol. 15, No. 5, pp. 621–627.

25. Fleming D.T., Wasserheit J.N. From epidemiological synergy to public health policy and practice: the contribution of other sexually transmitted diseases to sexual transmission of HIV infection. Sex. Transm. Infect., 1999, Vol. 75, No. 1, pp. 3–17.

26. Wasserheit J.N. Epidemiological synergy. Interrelationships between human immunodeficiency virus infection and other sexually transmitted diseases. Sex. Transm. Dis., 1992, Vol. 19, No. 2, pp. 61–77.

27. Korenromp E.L., de Vlas S.J., Nagelkerke N.J., Habbema J.D. Estimating the magnitude of STD cofactor effects on HIV transmission: how well can it be done? Sex. Transm. Dis., 2001, Vol. 28, No. 11, pp. 613–621.

28. Ghys P.D., Fransen K., Diallo M.O. et al. The associations between cervicovaginal HIV shedding, sexually transmitted diseases and immunosuppression in female sex workers in Abidjan, Côte d’Ivoire. AIDS, 1997, Vol. 11, No. 12, pp. F85–F93.

29. Röttingen J.-A., Cameron D.W., Garnett G.P. A systematic review of the epidemiologic interactions between classic sexually transmitted diseases and HIV: how much really is known? Sex. Transm. Dis., 2001, Vol. 28, No. 10, pp. 579–597.

30. Orroth K.K., White R.G., Korenromp E.L. et al. Empirical observations underestimate the proportion of human immunodeficiency virus infections attributable to sexually transmitted diseases in the Mwanza and Rakai sexually transmitted disease treatment trials: simulation results. Sex. Transm. Dis., 2006, Vol. 33, No. 9, pp. 536–544.

31. Nagot N., Ouedraogo A., Konate I. et al. Roles of clinical and subclinical reactivated herpes simplex virus type 2 infection and human immunodeficiency virus type 1 (HIV-1)-induced immunosuppression on genital and plasma HIV-1 levels. J. Infect. Dis., 2008, Vol. 198, No. 2, pp. 241–249.

32. Steen R., Wi T.E., Kamali A., Ndowa F. Control of sexually transmitted infections and prevention of HIV transmission: mending a fractured paradigm. Bull. World Health Organ., 2009, Vol. 87, No. 11, pp. 858–865.

33. Laga M., Alary M., Nzila N. et al. Condom promotion, sexually transmitted diseases treatment, and declining incidence of HIV-1 infection in female Zairian sex workers. Lancet, 1994, Vol. 344, No. 8917, pp. 246–248.

34. Grosskurth H., Gray R., Hayes R. et al. Control of sexually transmitted diseases for HIV-1 prevention: understanding the implications of the Mwanza and Rakai trials. Lancet, 2000, Vol. 355, No. 9219, pp. 1981–1987.

35. Grosskurth H., Mosha F., Todd J. et al. Impact of improved treatment of sexually transmitted diseases on HIV infection in rural Tanzania: randomised controlled trial. Lancet, 1995, Vol. 346, No. 8974, pp. 530–536.

36. Korenromp E.L., Bakker R., de Vias S.J. et al. HIV dynamics and behavior change as determinants of the impact of sexually transmitted disease treatment on HIV transmission in the context of the Rakai trial. AIDS, 2002, Vol. 16, No. 16, pp. 2209–2218.

37. Boily M.-C., Lowndes C., Alary M. The impact of HIV epidemic phases on the effectiveness of core group interventions: insights from mathematical models. Sex. Transm. Infect., 2002, Vol. 78, Suppl. I, pp. i78–i90.

38. Lowndes C.M., Alary M., Meda H. et al. Role of core and bridging groups in the transmission dynamics of HIV and STIs in Cotonou, Benin, West Africa. Sex. Transm. Infect., 2002, Vol. 78, Suppl. I, pp. i69–i77.

39. Kamali A., Quigley M., Nakiyingi J. et al. Syndromic management of sexually-transmitted infections and behaviour change interventions on transmission of HIV-1 in rural Uganda: a community randomised trial. Lancet, 2003, Vol. 361, No. 9358, pp. 645–652.

40. Kaul R., Kimani J., Nagelkerke N.J. et al. Monthly antibiotic chemoprophylaxis and incidence of sexually transmitted infections and HIV-1 infection in Kenyan sex workers: a randomized controlled trial. JAMA, 2004, Vol. 291, No. 21, pp. 2555–2562.

41. Watson-Jones D., Weiss H.A., Rusizoka M. et al. Effect of herpes simplex suppression on incidence of HIV among women in Tanzania. N. Engl. J. Med., 2008; 358 (15): 1560–1571.

42. Absalon J., Fuller C.M., Ompad D.C. et al. Gender differences in sexual behaviors, sexual partnerships, and HIV among drug users in New York City. AIDS Behav., 2006, Vol. 10, No. 6, pp. 707–715.

43. McCree D.H., Rompalo A.M. Biological and behavioral risk factors associated with STDs/HIV in women: implications for behavioral interventions. In: Behavioral interventions for prevention and control of sexually transmitted diseases. Eds. S.O.Aral, J.M.Douglas. New York: Springer, 2007. pp. 310–324.

44. Mitchell M.M., Latimer W.W. Gender differences in high risk sexual behaviors and injection practices associated with perceived HIV risk among injection drug users. AIDS Educ. Prev., 2009, Vol. 21, No. 4, pp. 384–394.

45. A guide for developing policies on the sexual and reproductive health and rights of young people in Europe. International Planned Parenthood Federation European Network. Brussels: IPPF EN, 2007, 68 р.

46. Журавлева И.В. Самосохранительное поведение подростков и заболевания, передающиеся половым путем // Социологические исследования. 2000. № 5. С. 66–74 [Zhuravleva I.V. Self-protective behavior of adolescents and sexually transmitted diseases. Sociological Research, 2000, No. 5, pp. 66–74 (In Russ.)].

47. Davis K.R., Weller S.C. The effectiveness of condoms in reducing heterosexual transmission of HIV. Fam. Plann. Perspect., 1999, Vol. 31, No. 6, pp. 272–279.

48. Scott-Sheldon L.A., Huedo-Medina T.B., Warren M.R. et al. Efficacy of behavioral interventions to increase condom use and reduce sexually transmitted infections: a meta-analysis. J. Acquir. Immune Defic. Syndr., 2011, Vol. 58, No. 5, pp. 489–498.

49. Sahasrabuddhe V.V., Vermund S.H. The future of HIV prevention: STI control and circumcision Interventions. Infect. Dis. Clin. North Am., 2007, Vol. 21, No. 1, pp. 241–257.

50. Gray R.H., Kigozi G., Serwadda D. et al. The effects of male circumcision on female partners’genital tract symptoms and vaginal infections in a randomized trial in Rakai, Uganda. Am. J. Obstet. Gynecol., 2009, Vol. 200, No. 1, pp. 42.e1–42.e7.

51. Auvert B., Sobngwi-Tambekou J., Cutler E. et al. Effect of male circumcision on the prevalence of high-risk human papillomavirus in young men: results of a randomized controlled trial conducted in Orange Farm, South Africa. J. Infect. Dis., 2009, Vol. 199, No. 1, pp. 14–19.

52. Рахматулина М.Р. Результаты изучения особенностей сексуального поведения несовершеннолетних различных социальных групп // Вестник дерматологии и венерологии. 2009. № 2. С. 13–19 [Rakhmatulina M.R. Results of the study of particular features of sexual behavior for underage teenagers belonging to different social groups. Bulletin of Dermatology and Venereology, 2009, No. 2, pp. 13–19 (In Russ.)].

53. Стеняева Н.Н., Бебнева Т.Н., Аполихина И.А., Куземин А.А. Сексуальное насилие в отношении несовершеннолетних: проблемы и пути решения // Consilium Medicum. 2012. № 1. С. 46–50 [Stenyaeva N.N., Bebneva T.N., Apolikhina I.A., Kuzemin A.A. Sexual abuse of minors: problems and solution approaches. Consilium Medicum, 2012, No. 1, pp. 46–50 (In Russ.)].

54. Epstein H., Morris M. Concurrent partnerships and HIV: an inconvenient truth. J. Int. AIDS Soc., 2011, Vol. 14, pp. 13–23.

55. Semple S.J., Strathdee S.A., Zians J., Patterson T.L. Correlates of trading sex for methamphetamine in a sample of HIV-negative heterosexual methamphetamine users. J. Psychoactive Drugs., 2011, Vol. 43, No. 2, pp. 79–88.

56. Corsi K.F., Booth R.E. HIV sex risk behaviors among heterosexual methamphetamine users: literature review from 2000 to present. Curr. Drug Abuse Rev., 2008, Vol. 1, No. 3, pp. 292–296.


Для цитирования:


Красносельских Т.В., Шаболтас А.В. МУЛЬТИДИСЦИПЛИНАРНЫЙ ПОДХОД К ПРОФИЛАКТИКЕ ИНФЕКЦИЙ, ПЕРЕДАВАЕМЫХ ПОЛОВЫМ ПУТЕМ, И ГЕМОКОНТАКТНЫХ ИНФЕКЦИЙ. ВИЧ-инфекция и иммуносупрессии. 2018;10(4):100-112. https://doi.org/10.22328/2077-9828-2018-10-4-100-112

For citation:


Krasnoselskikh T.V., Shaboltas A.V. MULTIDISCIPLINARY APPROACH TO THE PREVENTION OF SEXUALLY TRANSMITTED INFECTIONS AND BLOOD-BORNE INFECTIONS. HIV Infection and Immunosuppressive Disorders. 2018;10(4):100-112. (In Russ.) https://doi.org/10.22328/2077-9828-2018-10-4-100-112

Просмотров: 1400


Creative Commons License
Контент доступен под лицензией Creative Commons Attribution 4.0 License.


ISSN 2077-9828 (Print)