New coronoviral infection (COVID-19) combined with tuberculosis in patients at late stages of HIV infection with immunodeficiency
https://doi.org/10.22328/2077-9828-2021-13-1-80-87
Abstract
The study materials of 23 patients with COVID-19, combined with newly diagnosed tuberculosis at the late stages of HIV infection with an average CD4+ cells count not exceeding 30 cells/μl of blood and in the absence of antiretroviral therapy (the main group) and 23 patients with no COVID-19 (the comparison group) and the similar parameters are presented. The presence or absence of COVID-19 is characterized by social maladjustment, drug addiction, concomitant viral hepatitis B or C and COPD, generalized tuberculosis with extrapulmonary damage of various organs and the development of other opportunistic pulmonary infections, similar clinical and radiological manifestations, which can only be differentiated by microbiological and molecular genetic research methods. To prevent exogenous infection of the healthy population with COVID-19, it is imperative to organize an active regular examination of all patients with tuberculosis and HIV infection for COVID-19, especially at the later stages, in the TB care office for HIV-infected people at TB dispensaries.
About the Authors
A. V. Mishina
Moscow State University of Medicine and Dentistry named after A. I. Evdokimov, Ministry of Health of Russia; Central TB Research Institute
Russian Federation
Russian Federation
Moscow
V. Yu. Mishin
Moscow State University of Medicine and Dentistry named after A. I. Evdokimov, Ministry of Health of Russia; Central TB Research Institute; TB Clinical Hospital No 3 named after Prof. G. A. Zakharyin, Moscow Department of Health
Russian Federation
Russian Federation
Moscow
A. E. Ergeshov
Central TB Research Institute
Russian Federation
Russian Federation
Moscow
A. L. Sobkin
TB Clinical Hospital No 3 named after Prof. G. A. Zakharyin
Russian Federation
Russian Federation
Moscow
N. V. Sergeeva
TB Clinical Hospital No 3 named after Prof. G. A. Zakharyin
Russian Federation
Russian Federation
Moscow
S. V. Pilipenko
TB Clinical Hospital No 3 named after Prof. G. A. Zakharyin
Russian Federation
Russian Federation
Moscow
V. V. Romanov
Central TB Research Institute
Russian Federation
Russian Federation
Moscow
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Review
For citations:
Mishina A.V., Mishin V.Yu., Ergeshov A.E., Sobkin A.L., Sergeeva N.V., Pilipenko S.V., Romanov V.V. New coronoviral infection (COVID-19) combined with tuberculosis in patients at late stages of HIV infection with immunodeficiency. HIV Infection and Immunosuppressive Disorders. 2021;13(1):80-87. (In Russ.) https://doi.org/10.22328/2077-9828-2021-13-1-80-87
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