Наносистемы для доставки антиретровирусных лекарственных средств: возможности, проблемы и перспективы

Ведение пациентов с инфекцией, вызванной вирусом иммунодефицита человека (ВИЧ), сопровождается трудностями ранней диагностики, отсутствием специфической профилактики и дорогостоящим лечением. На данный момент от эпидемии, вызванной ВИЧ, от синдрома приобретенного иммунного дефицита (СПИД), умерло 32,7 млн человек по всему миру. Одним из наиболее важных направлений, позволяющих осуществлять контроль вирусной нагрузки и продлевать продолжительность жизни пациентов с ВИЧ, является наличие достаточного количества вариантов лечения ВИЧинфекции, доступных на  каждой стадии заболевания, что увеличивает эффективность терапии и позволяет избежать и/или минимизировать побочные эффекты лекарств.
Целью данной работы является обзор различных направлений в разработке новых лекарственных форм антиретровирусных средств на основе наносистем (НС) как препаратов, обладающих большей эффективностью для профилактики и лечения ВИЧ-инфекции.

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