Preview

HIV Infection and Immunosuppressive Disorders

Advanced search

Generalized HIV-associated kaposi's sarcoma with multiorgan lesion in a comorbid patient

https://doi.org/10.22328/2077-9828-2023-15-2-100-105

Abstract

An important role in a number of different clinical manifestations of HIV infection is played by the pathology of the skin and mucous membranes. Kaposi sarcoma (KS) is a multifocal malignant tumor of vascular origin with a predominant lesion of the skin and involvement of internal organs. Prior to the development of the HIV epidemic, KS was considered a rare tumor. Under conditions of increasing immunosuppression, HIV-associated KS tends to have a more severe course, generalization, and is accompanied by damage to visceral organs, leading to the death of patients. The authors demonstrate a clinical case of generalized KS with lesions of the skin, mucous membranes and internal organs (lungs) in a patient with HIV infection. The pulmonary form of KS is rare, but often leads to death.

About the Authors

A. A. Khryanin
Novosibirsk State Medical University; Association of obstetrician-gynecologists and dermatologists
Russian Federation

Novosibirsk



D. М. Kapustin
Novosibirsk State Medical University; Center for the Prevention and Control of AIDS, Clinical Hospital of Infectious Disease No. 1
Russian Federation

Novosibirsk



A. P. Nadeev
Novosibirsk State Medical University
Russian Federation

Novosibirsk



V. G. Sturov
V. Zelman Institute of medicine and psychology, Novosibirsk National Research State University
Russian Federation

Novosibirsk



E. V. Pushkarev
Novosibirsk State Medical University
Russian Federation

Novosibirsk



References

1. Belyakov N.A., Rassokhin V.V., Trofimova T.N. et al. Comorbid and severe forms of HIV infection in Russia. HIV infection and immunosuppression, 2016, Vol. 8, No. 3, рр. 9–25 (In Russ.). https://doi.org/10.22328/2077-9828-2016-8-3-9-25.

2. Khryanin A.A., Reshetnikov O.V. HIV infection in therapeutic practice. Moscow: Publishing house GEOTAR-Media, 2018. 88 p. (In Russ.).

3. Hengge U.R., Benninghoff B., Ruzicka T., Goos M. Topical immunomodulators — progress towards treating inflammation, infection, and cancer // Lancet. Infect Dis. 2001. No. 1. Р. 189–198.

4. Vally F., Selvaraj W., Ngalamika O. Admitted AIDS-associated Kaposi sarcoma patients. Indications for admission and predictors of mortality // Medicine (Baltimore). 2020. Vol. 99, No. 39. Р. e22415. doi: 10.1097/MD.0000000000022415.

5. Gasparetto T., Marchiori E., Lourenço S. et al. Pulmonary involvement in Kaposi sarcoma: correlation between imaging and pathology // Orphanet. J. Rare Dis. 2009. Vol. 4. Р. 18. doi: 10.1186/1750-1172-4-18.


Review

For citations:


Khryanin A.A., Kapustin D.М., Nadeev A.P., Sturov V.G., Pushkarev E.V. Generalized HIV-associated kaposi's sarcoma with multiorgan lesion in a comorbid patient. HIV Infection and Immunosuppressive Disorders. 2023;15(2):100-105. (In Russ.) https://doi.org/10.22328/2077-9828-2023-15-2-100-105

Views: 417


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2077-9828 (Print)