Health worker’s attitude, accessibility of health services and compliance with antiretroviral therapy in patients with HIV/AIDS: a cross-sectional study
https://doi.org/10.22328/2077-9828-2025-17-1-45-51
Abstract
The key to success in HIV treatment is compliance with antiretroviral therapy (ART). This is because continuous AR therapy can suppress HIV to undetectable levels, reduce the risk of drug resistance, improve quality of life and survival, improve overall health, and reduce the risk of HIV transmission. On the other hand, non-compliance with treatment can be a major cause of therapy failure.
The aim: to identify factors influencing compliance with ART therapy in patients with HIV/AIDS
Material and Methods. This study used a cross-sectional method. It involved 289 respondents as samples. The sample size was based on HSIEH formula (1989). Univariate analysis used frequency distribution to describe the percentage. Bivariate Logistic regression analysis (Adjusted OR and 95% confident interval) and multivariate analysis used Multiple logistic regression with Adjusted OR, 95% Confident Interval (CI), and a significant value of <0.05.
Results and discussion. Some factors had a significant relationship to the outcome, namely age with a p-value of <0.001 (95% CI 4.15–134.09), Occupation with a p-value of 0.002 (95% CI 2.7–32.7), Knowledge with a p-value <0.001 (95% CI 6.15– 43.8), attitude with a p-value of <0.001 (95% CI 3.37–43.8), accessibility of health services with a p-value of 0.004 (95% CI 1.5–9.4), and health worker’s attitudes with a p-value <0.001 (95% CI 1.88–9.21).
Conclusion. Another factor is also important, namely a good patient-provider relationship. Increasing patient trust through non-judgmental and supportive care and using positive motivational strategies can affect treatment compliance. Considering each measure taken is important to achieve optimal clinical outcomes and realize public health with preventive treatment
About the Authors
W. RahmadhaniIndonesia
Wulan Rahmadhani — Dr. of Public Health, Department of Midwifery, Faculty of Health Sciences
Yos Sudarso Street no 461, Gombong, Kebumen, Central Java
L. U. Na’mah
Indonesia
Lutfia Uli Na’mah — Magister of Health, Faculty of Health Sciences
Yos Sudarso Street no 461, Gombong, Kebumen, Central Java
U. L. Qomar
Indonesia
Umi Laelatul Qomar — Magister of Public Health, Faculty of Health Sciences
Yos Sudarso Street no 461, Gombong, Kebumen, Central Java
P. Chamroen
Cambodia
Pall Chamroen — Doctor of Public Health
References
1. World Health Organization. WHO | TB and HIV and other co-morbidities. WHO, 2020.
2. McKay E.A., Placencio-Castro M., Fu M.R., Fontenot H.B. Associations Between Sex Education Types and Sexual Behaviors Among Female Adolescents: a Secondary Data Analysis of the National Survey of Family Growth 2011–2019 // Sex. Res. Soc. Policy. 2022. Vol. 19, No. 3. doi: 10.1007/s13178-021-00664-w.
3. Vitalis D., Vilar-Compte M., Nyhan K., Pérez-Escamilla R. Breastfeeding inequities in South Africa: Can enforcement of the WHO Code help address them? — A systematic scoping review // International Journal for Equity in Health. 2021. doi: 10.1186/s12939-021-01441-2.
4. Asiedu А., A.J., F.R., A.M.S., A.E.F. Assessing community health nursing student’s knowledge and skills after equipping skills labs // Int. J. Gynecol. Obstet. 2018. Vol. 143, Suppl. 3.
5. Choi K.W. et al. Mapping a Syndemic of Psychosocial Risks During Pregnancy Using Network Analysis // Int. J. Behav. Med. 2019. Vol. 26, No. 2. P. 207–216. doi: 10.1007/s12529-019-09774-7.
6. World Health Organisation. WHO | HIV and youth. WHO, 2017.
7. Kemenkes R.I., Situasi umum HIV?AIDS dan Tes HIV // Pusat Data dan Informasi Kementrian Kesehatan RI. 2018.
8. Kemetrian Kesehatan Republik Indonesia. Вasic Health Research 2018, 2018.
9. Lee S.B., Valerius J. mHealth interventions to promote anti-retroviral adherence in HIV: Narrative review // JMIR mHealth and uHealth. 2020. Vol. 8, No. 8. doi: 10.2196/14739.
10. Putra D.S., Atmadani R.N., Hidayati I.R. Relationship between knowledge level of HIV/AIDS patient with antiretroviral adherence in primary healthcare service in Malang City // J. HIV/AIDS Soc. Serv. 2021. Vol. 20, No. 3. doi: 10.1080/15381501.2021.1961651.
11. Sasono T.N. Peran Warga Peduli Aids Cahaya Care Turen Dalam Meningkatkan Kualitas Hidup Odha // J. Kesehat. Mesencephalon. 2017. doi: 10.36053/mesencephalon.v3i1.37.
12. Wati N.S., Cahyo K., Indraswari R. Pengaruh Peran Warga Peduli Aids Terhadap Perilaku Pengaruh Peran Warga Peduli Aids Terhadap Perilaku Diskriminatif Pada Odha Pengaruh Peran Warga Peduli Aids Terhadap Perilaku // J. Kesehat. Masy. 2017.
13. Wahyuni S., Zulkifli A., Thamrin Y., Arsin A.A. The effect of counseling on adherence arv therapy in HIV/AIDS patient in H.A. sulthan daeng radja bulukumba regency // Enferm. Clin. 2020. Vol. 30. doi: 10.1016/j.enfcli.2019.10.101.
14. TH D.A., Kheru A., Marwan D. Hubungan Dukungan Keluarga Dan Tingkat Pendidikan Pasien Terhadap Kepatuhan Minum Obat Antiretroviral Pasien Hiv Aids Di Poli Rsud Dr. Drajat Prawiranegara Serang Banten // MAHESA Malahayati Heal. Student J. 2021. Vol. 1, No. 2. doi: 10.33024/mahesa.v1i2.3756.
15. Kensanovanto A., Perwitasari D.A. Tingkat kepatuhan dan keberhasilan terapi pada orang dengan penderita HIV/AIDS // Borobudur Pharm. Rev. 2022. Vol. 2, No. 2. doi: 10.31603/bphr.v2i2.7042.
16. Srikartika V.M., Intannia D., Aulia R. Faktor-Faktor yang Mempengaruhi Kepatuhan Pasien HIV/AIDS Rawat Jalan dalam Pengobatan Terapi Antiretroviral (ART) di Rumah Sakit Dr.H.Moch.Ansari Saleh Banjarmasin // J. Pharmascience. 2019. Vol. 6, No. 1. doi: 10.20527/jps.v6i1.6081.
17. Fardiana A., Nursalam N., Maulidiyah F. Intervention To Improve Antiretroviral Adherence And Quality Of Life On Hiv/Aids: A Systematic Review // Indones. J. Community Heal. Nurs. 2022. Vol. 7, No. 1. doi: 10.20473/ijchn.v7i1.39499.
18. Rahmadhani W., Aprina Н. Challenges of implementing the prevention of mother to child transmission (PMTCT) program // Int. J. Health Sci. (Qassim). 2022. doi: 10.53730/ijhs.v6ns5.8395.
19. Suryanto Y., Nurjanah U. Kepatuhan Minum Obat Anti Retro Viral (Arv) Pada Pasien Hiv/Aids // J. Ilmu Keperawatan Indones. 2021. Vol. 2, No. 1. doi: 10.57084/jikpi.v2i1.635.
20. Hayatiningsih A., Alam A., Sitorus T.D. Hubungan Lamanya Terapi ARV dengan Kepatuhan Minum Obat pada Anak HIV di Klinik Teratai // J. Sist. Kesehat. 2017. Vol. 3, No. 2. doi: 10.24198/jsk.v3i2.15007.
21. Kepatuhan Pasien Odha Meminum Obat Dengan Keberhasilan Terapi Antiretroviral (Arv) // J. Endur. 2022. Vol. 1, No. 2. doi: 10.22216/jen.v1i2.938.
22. A.W.D. Amanda Hubungan Dukungan Keluarga Dengan Kepatuhan Minum Obat Antiretroviral (ARV) Pada Pasien HIV/AIDS Di Balai BesarR Kesehatan Paru Masyarakat Makasar // Stikes Panakkukang Makassar Prodi S1-Keperawatan Prodi S1-Keperawatan Makassar. 2020.
23. Da Silva Oliveira R., Primeira M.R., Dos Santos W.M., de Paula C.C., S.M. de Mello Padoin. Association between social support and adherence to anti-retroviral treatment in people living with HIV // Rev. Gauch. Enferm. 2020. Vol. 41. doi: 10.1590/1983–1447.2020.20190290.
24. Oconnor C. et al. Risk factors affecting adherence to antiretroviral therapy among HIV patients in Manila, Philippines: A baseline cross-sectional analysis of the Philippines Connect for Life Study // Sex. Health. 2021. Vol. 18, No. 1. doi: 10.1071/SH20028.
25. Mlugu E.M., Minzi O., Kamuhabwa A.A.R. and Aklillu Е. Prevalence and correlates of asymptomatic malaria and anemia on first antenatal care visit among pregnant women in Southeast, Tanzania // Int. J. Environ. Res. Public Health. 2020. Vol. 17, No. 9. doi: 10.3390/ijerph17093123.
26. McMahon J.M. et al. Syndemic factors associated with adherence to antiretroviral therapy among HIV-positive adult heterosexual men // AIDS Res. Ther. 2019. Vol. 16, No. 1. doi: 10.1186/s12981-019-0248-9.
27. Hernández-Huerta D., Parro-Torres C., Madoz-Gúrpide A., Pérez-Elías M.J., Moreno-Guillén S., Ochoa-Mangado Е. Personality and adherence to antiretroviral therapy in HIV-infected adult patients // J. Psychosom. Res. 2021. Vol. 144. doi: 10.1016/j.jpsychores.2021.110413.
28. Wagman J.A. et al. Female Gender and HIV Transmission Risk Behaviors Among People Living with HIV Who Have Ever Used Injection Drugs in St. Petersburg, Russia // AIDS Behav. 2018. doi: 10.1007/s10461-018-2149-7.
29. Betancur M.N., Lins L., de Oliveira I.R., Brites C. Quality of life, anxiety and depression in patients with HIV/AIDS who present poor adherence to antiretroviral therapy: a cross-sectional study in Salvador, Brazil // Brazilian J. Infect. Dis. 2017. Vol. 21, No. 5. doi: 10.1016/j.bjid.2017.04.004.
30. Pourkazemi R., Janighorban M., Boroumandfar Z., Mostafavi F. A comprehensive reproductive health program for vulnerable adolescent girls // Reprod. Health. 2020. doi: 10.1186/s12978-020-0866-7.
31. Addo M.K., Aboagye R.G., Tarkang E.E. Factors influencing adherence to antiretroviral therapy among HIV/AIDS patients in the Ga West Municipality, Ghana // IJID Reg. 2022. Vol. 3. doi: 10.1016/j.ijregi.2022.04.009.
32. Ana J., Gobel F.A., Arman. Faktor yang Mempengaruhi Kepatuhan Terapi Antiretrovial pada Orang Dengan HIV di Yayasan Peduli Kelompok Dukungan Sebaya Kota Makassar // Wind. Public Heal. J. 2020. doi: 10.33096/woph.v1i3.85.
33. Rahmadhani W. The Affecting Factors of Implementation of Expanding Maternal and Neonatal Survival Program by the Ministry of Health of the Republic of Indonesia in Determining Midwifery in Kebumen, Central Java, Indonesia, 2021. doi: 10.4108/eai.18-11-2020.2311621.
34. Sigalingging N., Sitorus R.J., Flora R. Determinants of Adherence To Antiretroviral Therapy in Hiv/Aids Patients in Jambi // Media Kesehat. Masy. 2022. Vol. 4, No. 2.
35. Husna C. Analisis dukungan sosial dengan kepatuhan therapy antiretroviral (arv) pada pasien HIV/AIDS di Poliklinik Khusus RSUD. Dr. Zainoel Abidin Banda Aceh // J. Ilmu Keperawatan. 2013. Vol. 1, No. 1.
Review
For citations:
Rahmadhani W., Na’mah L.U., Qomar U.L., Chamroen P. Health worker’s attitude, accessibility of health services and compliance with antiretroviral therapy in patients with HIV/AIDS: a cross-sectional study. HIV Infection and Immunosuppressive Disorders. 2025;17(1):45-51. https://doi.org/10.22328/2077-9828-2025-17-1-45-51