ARE THERE SPECIAL FEATURES OF THE CLINICAL MANIFESTATIONS OF SYPHILIS IN HIV PATIENTS?

In the Russian Federation, the increasing prevalence of HIV is associated with a perpetually high prevalence of syphilis. The problem of the combined HIV/syphilis infection is addressed in sporadic publications in Russia; therefore, further studies are warranted. Study objective: To examine the clinical manifestations of syphilis in HIV patients. Materials and methods: 634 cases of syphilis, including 312 cases combined with syphilis and 322 cases of HIV monoinfection, were followed-up from Jan. 2006 through Dec. 2012 at the Stationary Hospital of Saint-Petersburg Municipal Dermatovenereologic Dispensary. Results: Among patients with the combine HIV/syphilis infection, the early clinical forms, including primary and secondary syphilis of the skin and mucosa and neurosyphilis, are predominant, whereas cryptic forms dominate among syphilis cases in general. HIV infection influences the clinical forms of early syphilis by promoting an earlier and more prevalent involvement of the central nervous system in the pathological process.

сифилис, ВИЧ-инфекция, клиника, коинфекция, syphilis, HIV infection, clinical features, coinfection

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