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THE USE OF HIV LOAD DETERNINATION FOR MONITORING THE QUALITY OF ANTIRETROVIRAL THERAPY IN SVERDLOVSK REGION

https://doi.org/10.22328/2077-9828-2016-8-2-17-22

Abstract

Study objectives: To assess the effectiveness of antiretroviral therapy in HIV patients living in Sverdlovsk Region, to examine the impact of operation of a multiprofessional team on the successfulness of antiretroviral therapy, and to study the 2-year dynamics of cases having undetectable HIV loads. Materials and methods: Based on digital database information, the virological effectiveness of ART in Sverdlovsk Region in 2013-2015 was assesses and the proportion of HIV patients having undetectable HIV loads was determined. The virological success was assumed to be a case where HIV load was found to below 50 copies per 1 mL of blood two times successively. Changed in the proportion of HIV patients having undetectable HIV loads were traced for two years. Results: In Sverdlovsk Region, the proportion of HIV patients having undetectable HIV load upon two successive tests was 63,9% and 70,6% in 2013 and 2015, respectively. The proportion of virological success cases varied in different territories from 80,1% (in Kamensk-Uralskiy) to 27,1% (in Degtiask) in 2013 and from 89,2% to 31,7% in 2015 in the same places. The operation of a multiprofessional team in a territory was associated with a higher proportion of HIV patients with suppressed viremia (68,6% and 76% where a multiprofessional team was present in 2013 and 2015, respectively, vs. 52,3% and 58,1% where no such team was organized). Conclusion: HIV load monitoring based on data included in a unified informa- tional system may be used to assess the quality of health care provided to HIV patients. The presence of a multiprofessional team correlated with higher rates of virological success. From 2013 to 2015, the proportion of HIV patients having undetectable HIV loads increased in Sverdlovsk Region.

About the Author

A. S. Podymova
Sverdlovsk Regional Center for Prevention and Control of AIDS and Infectious Diseases
Russian Federation


References

1. Cohen M.S., Chen Y.Q., McCauley M. Prevention of HIV-1 infection with early antiretroviral therapy // N. Engl. J. Med., 2011.- Vol. 365.- Р. 493-505.

2. Vital Signs: HIV Prevention Through Care and Treatment.- United States: Atlanta, GA: US Department of Health and Human Services, CDC.- December 2, 2011.- Vol. 60 (47).- Р. 1618-1623 (Available at http://www.cdc.gov/mmwr).

3. CDC. Behavioral Risk Factor Surveillance System Survey.- Atlanta, GA: US Department of Health and Human Services, CDC.- 2010 (Available at http://www.cdc.gov/brfss. Accessed October 25, 2011).

4. Torian L.V., Wiewel E.W. Continuity of HIV-related medical care, New York City, 2005-2009: do patients who initiate care stay in care? AIDS Patient Care STDS.- 2011.- Vol. 25.- Р. 79-88.

5. Tripathi A., Youmans E., Gibson J.J., Duffus W.A. The impact of retention in early HIV medical care on viro-immunological parameters and survival: a statewide study // AIDS Res. Hum. Retroviruses.- 2011.- Vol. 27.- Р. 751-758.

6. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. Recommendations for a public health approach.- WHO, June 2013.- Р. 22-28.


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For citations:


Podymova A.S. THE USE OF HIV LOAD DETERNINATION FOR MONITORING THE QUALITY OF ANTIRETROVIRAL THERAPY IN SVERDLOVSK REGION. HIV Infection and Immunosuppressive Disorders. 2016;8(2):17-22. (In Russ.) https://doi.org/10.22328/2077-9828-2016-8-2-17-22

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