DISPENSARY FOLLOWUP AND MEDICAL REHABILITATION OF TB/HIV CO- INFECTED PATIENTS
https://doi.org/10.22328/2077-9828-2018-10-3-80-89
Abstract
We have presented the data from a two-year dispensary follow-up carried out by a TB dispensary. We observed a cohort of 178 new TB patients co-infected with HIV. Out of them 79,8% were injecting drug users and suffered from viral hepatitis B and C; 86,5% did not receive antiretroviral therapy (ART); and 34,3% had CD4+ cell count less than 50 cells/μL of blood. Most common forms of TB were disseminated (28,8%) and infiltrative (30,5%) pulmonary TB; in 41,6% it was accompanied by extrapulmonary TB and in 29,2% — by other secondary diseases. Complex therapy resulted in clinical cure in 9% of patients in significant improvement in 53,9% of patients in 6,7% the disease was progressing and 30,3% of patients died during the follow-up. Disease progressing and lethal outcome were associated with low antiretroviral therapy adherence, drug addiction, severe and advanced pulmonary tuberculosis with extra pulmonary tuberculosis and other HIV-associated diseases.
About the Authors
V. Yu. Mishin
A.I.Evdokimov Moscow State University of Medicine and Dentistry;
Central TB Research Institute;
Government Budget Healthcare Establishment «Tuberculosis Clinical Hospital № 3 named after Prof. G.A.Zaharin» Department of Health of Moscow
Russian Federation
Moscow
Russian Federation
Moscow
A. V. Mishina
A.I.Evdokimov Moscow State University of Medicine and Dentistry;
Moscow Research and Clinical Center for Tuberculosis Control of Moscow Government Health Department
Russian Federation
Moscow
Russian Federation
Moscow
A. Е. Ergeshov
Central TB Research Institute
Russian Federation
Moscow
Russian Federation
Moscow
V. V. Romanov
Central TB Research Institute
Russian Federation
Moscow
Russian Federation
Moscow
A. L. Sobkin
Moscow Research and Clinical Center for Tuberculosis Control of Moscow Government Health Department
Russian Federation
Moscow
Russian Federation
Moscow
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For citations:
Mishin V.Yu., Mishina A.V., Ergeshov A.Е., Romanov V.V., Sobkin A.L. DISPENSARY FOLLOWUP AND MEDICAL REHABILITATION OF TB/HIV CO- INFECTED PATIENTS. HIV Infection and Immunosuppressive Disorders. 2018;10(3):80-89. (In Russ.) https://doi.org/10.22328/2077-9828-2018-10-3-80-89
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