TREATMENT OF PATIENTS AGAINST THE PULMONARY INVOLVEMENT IN THE CONDITIONS OF COMORBIDITY AT LATE DETECTION OF HIV INFECTION AND WITHOUT ART
https://doi.org/10.22328/2077-9828-2018-10-4-76-82
Abstract
Early diagnosis and effective treatment, including operative, in patients with comorbide conditions of pulmonary involvement affected by HIV infection with various infection ways is relevant. Materials and methods. Two clinical cases with pulmonary involvement in comorbidity conditions with the late detection of HIV infection and without antiretroviral therapy are presented. Results. It has been shown that a reduction in the high incidence of adverse outcomes of severe comorbid forms of the disease (in particular, a combination of HIV infection and tuberculosis) can be achieved by conducting an adequate monitoring of these patients, including secondary chemoprophylaxis of tuberculosis as well as, detection, treatment and prevention of co-infections and timely elimination of other possible risk factors (both social and medical). Conclusion. It is necessary to develop optimal algorithms and approaches of medical and psychosocial impact, focused on the initial period of treatment of patients with HIV infection (antiretroviral therapy, anti-tuberculosis therapy, prevention of opportunistic infections, etc.), since it is during this period that the greatest number of severe cases of the disease and adverse outcomes are observed.
About the Authors
G. A. Yakovlev
City Pokrovskaya Hospital
Russian Federation
Russian Federation
I. M. Uliukin
Military Medical Academy named after S.M.Kirov
Russian Federation
Russian Federation
E. S. Orlova
Military Medical Academy named after S.M.Kirov
Russian Federation
Russian Federation
V. V. Rassokhin
FSBSI HE I.P.Pavlov SPbSMU MON Russia;
FSBSI «IEM»
Russian Federation
Russian Federation
V. A. Gorichny
Military Medical Academy named after S.M.Kirov
Russian Federation
Russian Federation
References
1. Коломиец В.М. Дискуссионные вопросы химиопрофилактики туберкулеза у больных ВИЧ-инфекцией // Журнал инфектологии. 2016. Т. 8, № 4, Приложение. С. 8–12. [Kolomiets V.M. Discussion questions of chemoprophylaxis of tuberculosis in HIV-infected patients. Journal of Infectology, 2016, Vol. 8, No. 4, Suppl., pp. 8–12 (In Russ.)].
2. Ладная Н., Покровский В., Соколова Е. ВИЧ-инфекция в России сегодня // Демоскоп Weekly. 2014. № 599–600. URL: http://www.demoscope.ru/weekly/2014/0599/tema07.php. [Ladnaya N., Pokrovsky V., Sokolova E. HIV infection in Russia today. Demoscope Weekly, 2014, No. 599–600. URL: http://www.demoscope.ru/weekly/2014/0599/tema07.php (In Russ.)].
3. Зайцева Е.В., Даева Е.Ю., Лавров А.К., Свежанкина М.И., Лебедева Н.Ю. Особенности антиретровирусной и противотуберкулезной терапии у больных с сочетанием инфекций // ВИЧ-инфекция и иммуносупрессии. 2016. Т. 8, № 4. С. 86–87. [Zaitseva E.V., Daeva E.Yu., Lavrov A.K., Svezhankina M.I., Lebedeva N.Yu. Features of antiretroviral and antituberculous therapy in patients with a combination of infections. HIV Infection and Immunosuppressive Disorders, 2016, Vol. 8, No. 4, pp. 86–87 (In Russ.)].
4. Нечаева О.Б. Ситуация по туберкулезу и ВИЧ-инфекции в России // Туберкулез и болезни легких. 2014. Т. 92, № 6. С. 9–15 [Nechaeva О.B. The situation on tuberculosis and HIV infection in Russia. Tuberculosis and Lung Diseases, 2014, Vol. 92, No. 6, pp. 9–15 (In Russ.)].
5. Нечаева О.Б., Одинцов В.Е. Эпидемическая ситуация по туберкулезу и ВИЧ-инфекции в учреждениях уголовно-исполнительной системы России // Туберкулез и болезни легких. 2015. Т. 93, № 3. С. 36–41. [Nechaeva О.B., Оdintsov V.Е. [The epidemiological situation on tuberculosis and HIV infection in establishments of criminally-executive system of Russia. Tuberculosis and Lung Diseases, 2015, Vol. 93, No. 3, pp. 36–41 (In Russ.)].
6. Пантелеев А.М., Драчева М.С., Никулина О.В., Соколова О.С., Зонова А.В. Клинико-лабораторные особенности микобактериоза у больных ВИЧ-инфекцией // Журнал инфектологии. 2016. Т. 8, № 3. С. 40–45. [Panteleev A.M., Dracheva M.S., Nikulina O.V., Sokolova O.S., Zonova A.V. Clinical and laboratory features of atypical mycobacteriosis in HIV-patients. Journal of Infectology, 2016, Vol. 8, No. 3, pp. 40–45 (In Russ.)].
7. Покровский В.В., Юрин О.Г., Кравченко А.В., Беляева В.В., Ермак Т.Н., Канестри В.В., Шахгильдян В.И., Козырина В.Н., Буравцова В.В., Нарсия Р.С., Покровская А.В., Ефремова О.С., Коннов В.В., Куимова У.А., Попова А.А., Хохлова О.Н., Воронин Е.Е., Афонина Л.Ю., Васильева И.А., Зимина В.Н. Национальные рекомендации по диспансерному наблюдению и лечению больных ВИЧ- инфекцией. Клинический протокол // Эпидемиология и инфекционные болезни. Актуальные вопросы. 2015. № 6, Приложение. 120 с. [Pokrovsky V.V., Yurin O.G., Kravchenko A.V., Belyaeva V.V., Ermak T.N., Kanestri V.V., Shakhgildyan V.I., Kozyrina V.N., Buravtsova V.V., Narsia R.S., Pokrovskaya A.V., Efremova O.S., Konnov V.V., Kuimova U.A., Popova A.A., Khokhlova O.N., Voronin E.E., Afonina L.Yu., Vasil’eva I.A., Zimina V.N. National recommendations for dispensary observation and treatment of HIV affected patients. Epidemiology and Infectious Diseases. Actual Issues, 2015, No. 6, Suppl., 120 p. (In Russ.)].
8. Герцманн К., Ланге К. Туберкулез. В кн.: ВИЧ 2014/2015 / Под ред. К.Хоффмана, Ю.К.Роксштро. Hamburg: Medizin Fokus Verlag, 2014. С. 401–417. URL: http://hivlife.info/files/HAART/hivbook_2015_RUS.pdf [Herzmann Ch., Lange Ch. Tuberculosis. In: HIV 2014/2015. Eds. Ch.Hoffmann, J.K.Rockstroh. Hamburg: Medizin Fokus Verlag, 2014, pp. 401–417. URL: http://hivlife.info/files/HAART/ hivbook_2015_RUS.pdf (In Russ.)].
9. Jolley C.J., Bell J., Rafferty G.F., Moxham J., Strang J. Understanding Heroin Overdose: A Study of the Acute Respiratory Depressant Effects of Injected Pharmaceutical Heroin. PLoS One, 2015, Vol. 10, No.10, pp. e0140995.
10. Albion C., Shkrum M., Cairns J. Contributing factors to methadone-related deaths in Ontario. Am. J. Forensic Med. Pathol., 2010, Vol. 31, No. 4, pp. 313–319.
11. Sieniewicz D.J., Nidecker A.C. Conglomerate pulmonary disease: a form of talcosis in intravenous methadone abusers. Am. J. Roentgenol., 1980, Vol. 135, No. 4, pp. 697–702.
12. Pan P., Wei F., Jiang J., Liang B., Huang J., Liao Y., Su J., Li Y., Yang X., Chen H., Ye L., Liang H. Influence of Opiate Abuse on Expression of Toll-like Receptor 9 in Peripheral Blood Mononuclear Cells of HIV-1-Infected Individuals. Bing Du Xue Bao, 2015, Vol. 3, No. 2, pp. 132–138.
13. Трофимова Т.Н., Беляков Н.А., Рассохин В.В. Радиология и ВИЧ-инфекция. СПб.: Балтийский медицинский образовательный центр, 2017. 352 с. [Trofimova T.N., Belyakov N.A., Rassokhin V.V. Radiology and HIV Infection. Saint-Petersburg: Baltic medical educational center, 2017, 352 p. (In Russ.)].
Review
For citations:
Yakovlev G.A., Uliukin I.M., Orlova E.S., Rassokhin V.V., Gorichny V.A. TREATMENT OF PATIENTS AGAINST THE PULMONARY INVOLVEMENT IN THE CONDITIONS OF COMORBIDITY AT LATE DETECTION OF HIV INFECTION AND WITHOUT ART. HIV Infection and Immunosuppressive Disorders. 2018;10(4):76-82. (In Russ.) https://doi.org/10.22328/2077-9828-2018-10-4-76-82
Views:
1098
.png)
Email this article 