SEXUALLY-TRANSMITTED INFECTIONS IN HIV INFECTED PATIENTS
https://doi.org/10.22328/2077-9828-2019-11-1-71-74
Abstract
Sexually-transmitted infections are among the most well-known risk factors for HIV infection. The problem of combined diseases of STIs and HIV in infected people is represented by few works in the domestic scientific literature, therefore further study of this issue is required. Objective: to identify the prevalence of sexually transmitted infections in HIV-infected patients at the time of registration. Materials and methods. 49 clinical histories of patients with HIV infection were analyzed and studied at the Republican Center for the Prevention and Control of AIDS and Infectious Diseases of the Ministry of Health of the Republic of Tatarstan. Results. STIs with the prevalence of urogenital chlamydia, ureaplasmosis and mycoplasmosis in the oligosymptomatic clinical course were registered in 63% of patients (predominantly women — 67% of cases) with HIV infection in the natural infectious process course. Patients with HIV infection and syphilis showed lower level of CD4 lymphocytes and high levels of HIV RNA viral load.
About the Authors
E. R. ManapovaRussian Federation
V. H. Fazylov
Russian Federation
A. T. Beshimov
Russian Federation
References
1. Ward H., Ronn M. Contribution of sexually transmitted infections to the sexual transmission of HIV. Curr. Opin. HIV AIDS, 2010, Vol. 5, No. 4, pp. 305–310. URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2923028/.
2. Boily M.C., Baggaley R.F., Wang L. et al. Heterosexual risk of HIV-1 infection per sexual act: systematic review and metaanalysis of observational studies. Lancet Infect. Dis., 2009, Vol. 9, No. 2, pp. 118–129.
3. Aboud S., Msamanga G., Read J.S. et al. Genital tract infections among HIV-infected pregnant women in Malawi, Tanzania and Zambia. Int. J. STD AIDS, 2008, Vol. 19, No. 12, pp. 824–832.
4. Røttingen J.A., Cameron D.W., Garnett G.P. A systematic review of the epidemiologic interactions between classic sexually transmitted diseases and HIV: how much really is known? Sex. Transm. Dis., 2001, Vol. 28, pp. 579–597.
5. Grachanskaya L.V. Clinical and epidemiological characteristics and treatment of infections, sexually transmitted infections in HIV-infected patients. Extended abstract of candidate’s thesis: 14.01.10, Grachanskaya Larisa Vasil’evna. Kharkiv, 2006, 23 p. (In Russ.)
6. Strick L.B., Wald A., Celum C. Management of herpes simplex virus type 2 infection in HIV type 1-infected persons. Clin. Infect. Dis., 2006, Vol. 43, No. 3, pp. 347–356.
7. Ramaswamy M., Geretti A.M. Interactions and management issues in HSV and HIV coinfection. Exp. Rev. Anti Iinfect. Ther., 2007. Vol. 5, No. 2, pp. 231–243.
8. Buchacz K., Patel P., Taylor M. Syphilis increases HIV viral load and decreases CD4 cell counts in HIV-infected patients with new syphilis infections. AIDS, 2004, Vol. 18, pp. 2075–2079.
Review
For citations:
Manapova E.R., Fazylov V.H., Beshimov A.T. SEXUALLY-TRANSMITTED INFECTIONS IN HIV INFECTED PATIENTS. HIV Infection and Immunosuppressive Disorders. 2019;11(1):71-74. (In Russ.) https://doi.org/10.22328/2077-9828-2019-11-1-71-74