Preview

HIV Infection and Immunosuppressive Disorders

Advanced search

Medical and social features of patients with HIV-infection in combination with syphilis

https://doi.org/10.22328/2077-9828-2020-12-3-87-94

Abstract

Aim: to conduct analysis of morbidity with different forms of syphilis in Novosibirsk for the period from 2014 to 2018 and to study medical and social features of patients with syphilis and HIV-infection and to identify the main way of infection.

Materials and methods. In order to study the structure of syphilis morbidity in Novosibirsk Clinical Regional Dermatovenerologic Dispensary (SBHI NR NCRDD), the retrospective study of 2175 case histories of patients who had being hospitalized during the period of 2014 to 2018 was conducted.

Results and discussions. 3.4% of patients being hospitalized suffer from syphilis. Herewith, newly diagnosed HIV-infection was found in 21.3% of patients. Half the patients are of socially disadvantaged backgrounds characterized by risky sexual behavior. Authors presented medical and social, and psychological profile of patients with syphilis and HIV-coinfection. Obtained results may be used for developing effective programs of prophylaxis and treatment of specified diseases.

About the Authors

A. A. Khryanin
Novosibirsk State Medical University; Association of Obstetricians-Gynecologists and Dermatovenerologists
Russian Federation

Aleksey A. Khryanin

Novosibirsk



T. A. Spyx
Novosibirsk State Medical University
Russian Federation

Tatyana A. Spyx

Novosibirsk



M. V. Russkikh
Novosibirsk State Medical University
Russian Federation

Maria V. Russkikh

Novosibirsk



F. A. Sukharev
Novosibirsk State Medical University
Russian Federation

Filipp A. Sukharev

Novosibirsk



I. O. Marinkin
Novosibirsk State Medical University
Russian Federation

Igor O. Marinkin

Novosibirsk



References

1. Kubanova A.A., Kubanov A.A., Melekhina L.E. Syphilis incidence in the Russian Federation for the period 2006–2016. Bulletin of Dermatology and Venereology, 2017, No. 5, рр. 16–25 (In Russ.). doi: 10.25208/0042-46092017-93-5-16-25.

2. Kubanova A.A., Kubanov A.A., Melekhina L.E., Bogdanova E.V. Syphilis incidence in the Russian Federation for the period 2010–2014. Bulletin of Dermatology and Venereology, 2015, No. 5, рр. 15–23 (In Russ.). doi: 10.25208/0042-4609-2015-0-5-15-23.

3. Wang X., Lan G., Shen Z., Vermund S.H., Zhu Q., Chen Y., Khoshnood K., Wu Z., Tang Z. HIV and syphilis prevalence trends among men who have sex with men in Guangxi, China: yearly cross-sectional surveys, 2008–2012 // BMC Infectious Diseases. 2014. No. 14. Р. 367.

4. Chesson H.W., Pinkerton S.D., Voigt R., Counts G.W. HIV infections and associated costs attributable to syphilis co-infection among African Americans // Am. J. Public Health. 2013. Vol. 93, No. 6. Р. 943–948.

5. Ghanem K.G., Moore R.D., Rompalo A.M., Erbelding E.J., Zenilman J.M., Gebo K.A. Neurosyphilis in a clinical cohort of HIV-1-infected patients // AIDS. 2008. Vol. 22, No. 10. Р. 1145–1151.

6. Chumakov E.M., Petrova N.N., Rassokhin V.V. Mental disorders and their impact on adherence in HIV-infected patients with early syphilis. HIV infection and immunosuppression, 2018, Vol. 10, No. 2, рр. 69–80 (In Russ.). doi: 10.22328/2077-9828-2018-10-2-69-80.

7. Martinelli C.V., Tognetti L., Colao G., Syphilis with HIV in Florence, 2003–2009: a 7-year epidemiological study // Epidemiol. Infect. 2012. Vol. 140, No. 1. P. 168–171.

8. Krasnoselskikh T.V., Manasheva E.B., Gezei M.A. Comorbidity of syphilis and HIV infection: negative epidemiological and clinical synergism. HIV infection and immunosuppression, 2018, Vol. 10, No. 3, рр. 7–16 (In Russ.). doi: 10.22328/2077-9828-2018-10-3-7-16.

9. Kozenko L.I., Lin V.N., Kiriutsov A.M. Identification of HIV infection in patients with syphilis. Bulletin of Dermatology and Venereology, 2004, No. 4, рр. 56 (In Russ.).

10. Korobko A.V., Orlova I.A., Smirnova N.V., Dudko V.Yu., Smirnova I.O., Smirnova T.S., Litvinenko I.V., Pyriatinskaya A.B., Sevashevich A.V., Gaivoronskaya O.V., Ivanov A.M. Syphilis in patients with HIV infection — the importance of medical and social factors in the development of co-infection. HIV infection and immunosuppression, 2014, Vol. 6, No. 4, рр. 57–63 (In Russ.). doi: 10.22328/2077-9828-2014-6-4-57-63.

11. Stasenko V.L., Pitsenko N.D., Pasechnik O.A., Blokh A.I. Prevalence of HIV infection among injecting drug users in the Siberian region. Modern problems of science and education, 2017, No. 1, р. 8. (In Russ.).

12. Krasnoselskikh T.V., Sokolovsky E.V. Strategies and methodological bases for the prevention of sexually transmitted infections in subpopulations of increased behavioral risk of infection. Bulletin of Dermatology and Venereology, 2016, No. 1, рр. 21–31 (In Russ.). doi: 10.25208/0042-4609-2016-0-1-21-31.

13. Musatov V.B., Yakovlev A.A., Chaika N.A., Kelly D., Amirkhanyan Yu.A. The main reasons and modern methods for correcting low adherence to antiretroviral therapy in difficult patients. HIV infection and immunosuppression, 2018, Vol. 10, No. 4, рр. 37–56 (In Russ.). doi: 10.22328/2077-9828-2018-10-4-37-56.


Review

For citations:


Khryanin A.A., Spyx T.A., Russkikh M.V., Sukharev F.A., Marinkin I.O. Medical and social features of patients with HIV-infection in combination with syphilis. HIV Infection and Immunosuppressive Disorders. 2020;12(3):87-94. (In Russ.) https://doi.org/10.22328/2077-9828-2020-12-3-87-94

Views: 931


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2077-9828 (Print)