The effectiveness of treatment of newly diagnosed and relapsed tuberculosis with HIV infection in a medical and correctional institution
https://doi.org/10.22328/2077-9828-2025-17-4-81-86
Abstract
The aim. To clarify the effectiveness of treatment for newly diagnosed and relapsed tuberculosis combined with HIV infection in patients in places of imprisonment.
Materials and methods. 327 patients (men) with tuberculosis and HIV infection stages 4B, 4C and 5: Group 1 — 72.2% (n=262) with newly diagnosed tuberculosis, Group 2 — 17.9% (n=65) with relapse. To analyze the effectiveness of treatment, χ2 was calculated with Yates correction for continuity between the indicators of the groups by treatment quarters.
Results and discussion. In the first 3 months of treatment, bacterial excretion by sputum microscopy ceased in 41.7% (48/115) and 33.3% (11/33), in the 12th month of treatment in 63.5% (73/115) and 57.6% (19/33); in the first 3 months of treatment, bacterial excretion by sputum culture ceased in 42.4% (72/170) and 42.0% (21/50), in the 12th month of treatment in 67.6% (115/170) and 62.0% (31/50); In the first 3 months of treatment, closure of decay cavities occurs in 26.5% (31/117) and 26.7% (12/45), in the 12th month of treatment in 64.1% (75/117) and 55.6% (25/45) of newly diagnosed tuberculosis, respectively.
Conclusion. In patients with tuberculosis combined with HIV infection in an anti-tuberculosis institution of the penitentiary service of Russia, the effectiveness of treatment for newly diagnosed and relapsed disease is practically the same.
About the Author
V. S. Borovitsky
Research Institute of the Federal Penitentiary Service
Russian Federation
Russian Federation
Borovitsky Vladislav Semenovich
Moscow
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For citations:
Borovitsky V.S. The effectiveness of treatment of newly diagnosed and relapsed tuberculosis with HIV infection in a medical and correctional institution. HIV Infection and Immunosuppressive Disorders. 2025;17(4):81-86. (In Russ.) https://doi.org/10.22328/2077-9828-2025-17-4-81-86
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