Analysis of strategies for optimizing medical care for patients with chronic hepatitis C in the Arkhangelsk region

Chronic hepatitis C (HCV-infection) continues to be a serious medical, social and economic problem worldwide, which requires improved approaches to its diagnosis, treatment and prevention.
The aim of the study: to create prognostic models of the epidemic situation of chronic hepatitis C in the Arkhangelsk region and their pharmacoeconomic assessment to select the optimal strategy for providing medical care to HCV-infected patients.
Materials and methods. To build prognostic models of the development of the epidemiological situation of chronic hepatitis C, a mathematical model, that was developed and described by Razavi H. et al. was used.
Results and discussion. According to calculations of the mathematical model, while maintaining existing approaches to the diagnosis and treatment of chronic hepatitis C, the number of infected people in the Arkhangelsk region will continue to grow and will reach up to 27,080 people by 2030. With timely measures to expand the availability of antiviral therapy for the population, it is possible to achieve WHO-recommended targets by 2030 to reduce the number of new infections by 90% and deaths from HCV-infection by 65%.
Conclusion. We have shown that the WHO strategy is the most appropriate scenario for providing medical care to patients with chronic hepatitis C, as it significantly reduces the burden of this disease in the Arkhangelsk region.

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