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ВИЧ-инфекция и иммуносупрессии

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МУЖСКОЙ ГИПОГОНАДИЗМ НА ФОНЕ ВИЧ-ИНФЕКЦИИ

https://doi.org/10.22328/2077-9828-2016-8-1-7-18

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Аннотация

Гипогонадизм встречается у 15-25% ВИЧ-инфицированных мужчин. По происхождению гипогонадизм чаще является гипогонадотропным, реже имеет тестикулярную этиологию. Помимо нарушения половой функции, для больных гипогонадизмом характерны: депрессия, анемия, снижение мышечной и костной массы. При отсутствии противопоказаний лечение проводится препаратами тестостерона или гонадотропинами. Осложнения при терапии препаратами тестостерона проявляются в виде гиперплазии простаты, увеличения риска развития рака предстательной железы, полицитемии и апноэ во сне, причем риск этих осложнений увеличивается с возрастом пациентов. Скрининг на гипогонадизм проводится среди пациентов при наличии эректильной дисфункции и депрессивных состояний и заключается в определении уровня тестостерона и глобулина, связывающего половые стероиды.

Об авторах

Дария Михайловна Сурженко
Санкт-Петербургский центр по профилактике и борьбе со СПИД и инфекционными заболеваниями; Институт эволюционной физиологии и биохимии им. И.М.Сеченова РАН
Россия


Валерий Владимирович Кузик
Институт эволюционной физиологии и биохимии им. И.М.Сеченова РАН
Россия


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Для цитирования:


Сурженко Д.М., Кузик В.В. МУЖСКОЙ ГИПОГОНАДИЗМ НА ФОНЕ ВИЧ-ИНФЕКЦИИ. ВИЧ-инфекция и иммуносупрессии. 2016;8(1):7-18. https://doi.org/10.22328/2077-9828-2016-8-1-7-18

For citation:


Surzhenko D.M., Kuzik V.V. HIV-ASSOCIATED MALE HYPOGONADISM. HIV Infection and Immunosuppressive Disorders. 2016;8(1):7-18. (In Russ.) https://doi.org/10.22328/2077-9828-2016-8-1-7-18

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