SING MOLECULAR EPIDEMIOLOGICAL METHODS TO INVESTIGATE HIV BREAKOUTS AMONG INJECTION DRUG USERS
https://doi.org/10.22328/2077-9828-2016-8-4-66-74
Abstract
The objective of the present study was to investigate HIV outbreaks among injection drug users in Minsk using molecular epidemiological approaches and to find the phylogenetic relationships between HIV isolates from different patients in order to determine common HIV infection sources. Phylogenetic analysis showed that HIV outbreaks among IDUs in Minsk were caused by HIV entries from different sources. At least seven IDU groups were distinguished. It was also found that hepatitis C virus was in most cases present in the IDUs before they became HIV infected. In two cases, HIV patients acquired hepatitis B virus from the same source.
Keywords
ВИЧ,
ВИЧ-инфекция,
ВГС,
ПИН,
секвенирование,
филогенетический анализ,
HIV,
HIV infected,
HCV,
IDUs,
sequencing,
phylogenetic analysis
About the Authors
V. F. Eremin
The Republican Research and Practical Center for Epidemiology and Microbiology
Russian Federation
Russian Federation
E. L. Gasich
The Republican Research and Practical Center for Epidemiology and Microbiology
Russian Federation
Russian Federation
S. V. Sosinovic
The Republican Research and Practical Center for Epidemiology and Microbiology
Russian Federation
Russian Federation
P. N. Yurovsky
The Republican Research and Practical Center for Epidemiology and Microbiology; Republican Centre for Hygiene, Epidemiology and Public Health
Russian Federation
Russian Federation
E. G. Fisenko
Republican Centre for Hygiene, Epidemiology and Public Health
Russian Federation
Russian Federation
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Review
For citations:
Eremin V.F., Gasich E.L., Sosinovic S.V., Yurovsky P.N., Fisenko E.G. SING MOLECULAR EPIDEMIOLOGICAL METHODS TO INVESTIGATE HIV BREAKOUTS AMONG INJECTION DRUG USERS. HIV Infection and Immunosuppressive Disorders. 2016;8(4):66-74. (In Russ.) https://doi.org/10.22328/2077-9828-2016-8-4-66-74
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