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Application of real-time PCR for the quantitative determination of TREC and KREC molecules in the blood of HIV-infected patients

About the Authors

M. A. Saitgalina
St. Petersburg Pasteur Research Institute of Epidemiology and Microbiology
Russian Federation

St. Petersburg



Yu. V. Ostankova
St. Petersburg Pasteur Research Institute of Epidemiology and Microbiology
Russian Federation

St. Petersburg



References

1. Tangye S.G., Al-Herz W., Bousfiha A., Chatila T., Cunningham-Rundles C., Etzioni A. Human inborn errors of immunity: 2019 update on the classification from the international union of immunological societies expert committee // J. Clin. Immunol. 2020. Vol. 40, No. 1. Р. 24–64. doi: 10.1007/s10875-019-00737-x.

2. Hazenberg M.D., Verschuren M.C., Hamann D., Miedema F., van Dongen J.J. T cell receptor excision circles as markers for recent thymic emigrants: basic aspects, technical approach, and guidelines for interpretation // J. Mol. Med. 2001. No. 79. Р. 631–640. doi: 10.1007/s001090100271.

3. Serana F., Chiarini M., Zanotti C., Sottini A., Bertoli D., Bosio A. et al. Use of V(D)J. recombination excision circles to identify T- and B-cell defects and to monitor the treatment in primary and acquired immunodeficiencies // J. Transl. Med. 2013. Vol. 119. Р. 1–11. doi: 10.1186/1479-5876-11-119.

4. Saitgalina M.A., Ostankova Yu.V., Lyubimova N.E., Semenov A.V., Kuznetsova R.N., Totolyan A.A. Modified method for quantitative determination of TREC and KREC levels in peripheral blood in patients with immunodeficiency conditions. Infection and Immunity. 2022. Т. 12, No 5. (In Russ.). doi: 10.15789/2220-7619-MMF-2039.


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For citations:


Saitgalina M.A., Ostankova Yu.V. Application of real-time PCR for the quantitative determination of TREC and KREC molecules in the blood of HIV-infected patients. HIV Infection and Immunosuppressive Disorders. 2023;15(1):82-83. (In Russ.)

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ISSN 2077-9828 (Print)