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HIV Infection and Immunosuppressive Disorders

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Еxperience of beginning antiretroviral therapy in a military medical organization

https://doi.org/10.22328/2077-9828-2024-16-4-73-80

Abstract

Military personnel constitute a separate cohort of the population with characteristic features of the spread and course of HIV infection associated with military life, the nature and physiology of military labor. At the same time, it is assumed that more than 2.2% of the male population of mobilization age in Russia are HIV affected.

The aim: analysis and generalization of the experience of the infectious diseases clinic of the Military Medical Academy in prescribing antiretroviral therapy.

Material and methods included all case histories of patients who were hospitalized in the clinic from March 2022 to September 2024 with a diagnosis of HIV infection (n=107). At the second stage of the study, cases requiring antiretroviral therapy were selected (n=42).

Results and discussion. 88% of patients were in the stage of secondary diseases of HIV infection. Severe immunodeficiency according to the classification of immune disorders of the World Health Organization was determined in 83,3%. The average CD4+ lymphocyte level was 151±49 cells/μl (11.3±2.9%). The most frequently prescribed antiretroviral therapy regimen was a combination of lamivudine, tenofovir and dolutegravir.

Conclusion. A distinctive feature of military medical organizations is the inclusion of infectious disease departments as structural units, which distinguishes them from civilian multidisciplinary hospitals in terms of patient’ integrated management. It has become possible to simultaneously provide medical care to polymorbid patients by a multidisciplinary team in the conditions of a single medical organization. The experience of departmental medicine can be useful in providing high-quality medical care to the civilian population.

About the Authors

K. V. Kozlov
Military Medical Academy
Russian Federation

St. Petersburg



M. A. Bulygin
Military Medical Academy
Russian Federation

St. Petersburg



V. D. Shamigulov
Military Medical Academy; 1472 Navy Clinical Hospital
Russian Federation

St. Petersburg

Sevastopol



K. D. Kicherov
Military Medical Academy
Russian Federation

St. Petersburg



O. V. Maltsev
Military Medical Academy
Russian Federation

St. Petersburg



D. M. Shakhmanov
Military Medical Academy
Russian Federation

St. Petersburg



Yu. I. Bulan’kov
Military Medical Academy; Saint Petersburg Medico-Social Institute
Russian Federation

St. Petersburg



I. M. Uliukin
Military Medical Academy
Russian Federation

St. Petersburg



Yu. I. Lyashenko
Military Medical Academy
Russian Federation

St. Petersburg



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Review

For citations:


Kozlov K.V., Bulygin M.A., Shamigulov V.D., Kicherov K.D., Maltsev O.V., Shakhmanov D.M., Bulan’kov Yu.I., Uliukin I.M., Lyashenko Yu.I. Еxperience of beginning antiretroviral therapy in a military medical organization. HIV Infection and Immunosuppressive Disorders. 2024;16(4):73-80. (In Russ.) https://doi.org/10.22328/2077-9828-2024-16-4-73-80

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